3-Pyridyl bromide

3-Pyridyl bromide
  • CAS No.:626-55-1
Other grades of this product :
3-Pyridyl bromide Basic information
Product Name:3-Pyridyl bromide
Synonyms:Pyridine, 3-bromo-;5-BROMO PYRIDINE;3-BROMOPYRIDINE;3-pyridyl bromide;AURORA KA-875;TIMTEC-BB SBB003998;3-bromo-pyridin;3-Bromopyridine 5-Bromo Pyridine
CAS:626-55-1
MF:C5H4BrN
MW:158
EINECS:210-952-0
Product Categories:The intermediate of Abiraterone & antidepressant Zimeldine Dihydrochloride;alkyl bromide;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Aromatics;Pyridine;Pyridine series;Pyridines;Bromine Compounds;Miscellaneous Compounds;Bromopyridines;Halopyridines;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;1;chem002;bc0001
Mol File:626-55-1.mol
3-Pyridyl bromide Chemical Properties
Melting point -27°C
Boiling point 173 °C (lit.)
density 1.64 g/mL at 25 °C (lit.)
vapor pressure 1.64hPa at 25℃
refractive index n20/D 1.571(lit.)
Fp 125 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility 31g/l
form Liquid
pka2.84(at 25℃)
Specific Gravity1.617
color Clear colorless to yellow or slightly brown
Water Solubility Soluble in water (31 g/L at 20°C).
BRN 105880
InChIKeyNYPYPOZNGOXYSU-UHFFFAOYSA-N
LogP1.694
CAS DataBase Reference626-55-1(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 3-bromo-(626-55-1)
EPA Substance Registry System3-Bromopyridine (626-55-1)
Safety Information
Hazard Codes Xn,T,F,Xi
Risk Statements 10-22-36/37/38-23/24/25-20/21/22
Safety Statements 26-45-38-36/37/39-28A-16
RIDADR UN 1993 3/PG 3
WGK Germany 3
8
Hazard Note Toxic/Flammable/Irritant
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29333999
MSDS Information
ProviderLanguage
3-Pyridyl bromide English
ACROS English
SigmaAldrich English
ALFA English
3-Pyridyl bromide Usage And Synthesis
Chemical PropertiesCLEAR COLOURLESS TO YELLOW LIQUID
UsesPyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita.
Uses3-Bromopyridine undergoes lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines.
DefinitionChEBI: A monobromopyridine in which the bromo substituent is located at position 3.
Synthesis Reference(s)Synthesis, p. 293, 1974 DOI: 10.1055/s-1974-23300

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