Product

2-Acetyl-6-methoxynaphthalene

CAS No.：3900-45-6

Other grades of this product :

2-Acetyl-6-methoxynaphthalene Basic information

Product Name:	2-Acetyl-6-methoxynaphthalene
Synonyms:	1-(6-Methoxy-2-naphehalenyl)ethanone;6-ACETYL-2-METHOXYNAPHTHALENE;6-Methoxy-2-acetyInaphthalene;2-Acetyl-6-Methoxynaphthalene, 98% 10GR;1-(6-Methoxy-2-naphthalenyl)ethanone;1-(2-Methoxynaphthalen-6-yl)ethanone;2'-Acetonaphthone, 6'-Methoxy- (6CI,7CI,8CI);NSC 105564
CAS:	3900-45-6
MF:	C13H12O2
MW:	200.23
EINECS:	223-453-8
Product Categories:	Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Miscellaneous;C13 to C14;Carbonyl Compounds;Ketones;Aromatics;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	3900-45-6.mol

2-Acetyl-6-methoxynaphthalene Chemical Properties

Melting point	107-109 °C(lit.)
Boiling point	155-160°C 0,4mm
density	1.0907 (rough estimate)
vapor pressure	0.009Pa at 25℃
refractive index	1.5906 (estimate)
Fp	155-160°C/0.4mm
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Powder
color	Light yellow-beige
Water Solubility	760mg/L at 27℃
BRN	1871098
LogP	1.52 at 27℃
CAS DataBase Reference	3900-45-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	37/38-36/37/38
Safety Statements	37/39-26-36/37
WGK Germany	3
Hazard Note	Irritant
HS Code	29145000

MSDS Information

Provider	Language
1-(6-Methoxy-2-naphthyl)ethan-1-one	English
ACROS	English
SigmaAldrich	English
ALFA	English

2-Acetyl-6-methoxynaphthalene Usage And Synthesis

Chemical Properties	Light yellow-beige powder
Uses	Naproxen impurity L.
Uses	Naproxen impurity L. Naproxen USP Related Compound L
General Description	6′-Methoxy-2′-acetonaphthone (6-methoxy-2-naphthylacetic acid ) is metabolite of nabumetone, a phototoxic nonsteroidal antiinflammatory drug.1
Flammability and Explosibility	Nonflammable

2-Acetyl-6-methoxynaphthalene Preparation Products And Raw materials

Raw materials

Ethanol-->Methanol-->Sulfuric acid-->Aluminum chloride-->Acetyl chloride-->2-Naphthol-->Nitrobenzene-->2-Methoxynaphthalene-->1-(6-methoxy-1-naphthyl)ethan-1-one-->2-Naphthaleneacetic acid, 6-methoxy-α-methylene-, methyl ester-->2-ETHYNYL-6-METHOXYNAPHTHALENE 97-->6-METHOXY-2-(1-METHYLVINYL)NAPHTHALENE-->2-Methoxy-1-acetonaphthone-->2-ACETYL-5-BROMO-6-METHOXYNAPHTHALENE-->(+/-)-2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID

Preparation Products

ETHYL 3-(6-METHOXY-2-NAPHTHYL)-3-METHYL GLYCIDATE-->METHYL 3-(6-METHOXY-2-NAPHTHYL)-3-METHYL GLYCIDATE-->Naproxen-->6-methoxy-alpha-methylnaphthalen-1-acetaldehyde-->6-ETHYL-2-METHOXYLNAPHTHALINE

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