Other grades of this product :
| 2-Chloro-4-amino-6,7-dimethoxyquinazoline Basic information |
| 2-Chloro-4-amino-6,7-dimethoxyquinazoline Chemical Properties |
| Melting point | 262-268 °C (dec.)(lit.) | | Boiling point | 374.0±42.0 °C(Predicted) | | density | 1.5062 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.5500 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO (Sparingly, Heated), Methanol (Slightly, Heated) | | form | neat | | pka | 4.35±0.30(Predicted) | | color | White to Off-White | | Water Solubility | 1.418g/L at 25℃ | | BRN | 747463 | | LogP | 1.5 at 25℃ | | CAS DataBase Reference | 23680-84-4(CAS DataBase Reference) | | NIST Chemistry Reference | 4-Amino-2-chloro-6,7-dimethoxyquinazoline(23680-84-4) |
| 2-Chloro-4-amino-6,7-dimethoxyquinazoline Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Intermediate in the production on Terazosin. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031 | | Flammability and Explosibility | Nonflammable |
| 2-Chloro-4-amino-6,7-dimethoxyquinazoline Preparation Products And Raw materials |
| Raw materials | Urea, N-cyano-N'-(3,4-dimethoxyphenyl)--->4-Quinazolinamine, 2-chloro-5-iodo-6,7-dimethoxy--->157459-53-5-->6,7-Dimethoxyquinazoline-2,4-dione-->3,4-DIMETHOXY-6-NITROBENZAMIDE-->4,5-Dimethoxy-2-nitrobenzoic acid-->4-Aminoveratrole-->2-AMINO-4,5-DIMETHOXYBENZAMIDE-->2,4-Dichloroquinazoline-->Methyl 3,4-dimethoxybenzoate-->2,4-Dichloro-6,7-dimethoxyquinazoline-->Methyl 2-amino-4,5-dimethoxybenzoate-->Methyl 4,5-dimethoxy-2-nitrobenzoate | | Preparation Products | Alfuzosin |
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