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| Iminostilbene Basic information |
| Product Name: | Iminostilbene | | Synonyms: | 2,3,6,7-Dibenzazepine;5-Azadibenzo(a,e)cycloheptatriene;Iminostibene carbonyl chloride;5H-Dibenz[b,f]azepine;Iminostilbene;o,o'-Iminostilbene;IMINOSTILBENECARBAMAZEPINE;11H-Benzo[b][1]benzazepine | | CAS: | 256-96-2 | | MF: | C14H11N | | MW: | 193.24 | | EINECS: | 205-970-0 | | Product Categories: | Heterocyclic Compounds;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Stilbenes (substituted);Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;N-Containing;Others;Pharmaceutical raw material;Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 256-96-2.mol |
| Iminostilbene Chemical Properties |
| Melting point | 197 °C | | Boiling point | 221 °C(lit.) | | density | 1.290 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.523(lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | dioxane: 50 mg/mL, clear | | form | powder | | pka | 1.71±0.20(Predicted) | | color | yellow to orange | | Water Solubility | Soluble in ethyl acetate (25 mg/ml), water (partly), dioxane, chloroform, and DMSO. | | BRN | 1343358 | | LogP | 4.06 | | CAS DataBase Reference | 256-96-2(CAS DataBase Reference) | | NIST Chemistry Reference | o,o'-Iminostilbene(256-96-2) | | EPA Substance Registry System | 5H-Dibenz[b,f]azepine (256-96-2) |
| Iminostilbene Usage And Synthesis |
| Chemical Properties | Yellow to orange-yellow fine powder | | Uses | Iminostilbene is mainly used as a pharmaceutical intermediate for the production of carbamazepine, Oxcarbazepine, and rhodium catalyst ligand. It is a metabolite of of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain. | | Application | Iminostilbene has good antioxidant effects. N-acetyl iminostilbene was synthesized by incubating iminostilbene (2.0020 g, 10.360 mmol) with acetic anhydride. | | Preparation | iminostilbene synthesis: 10,11-Dihydro-5-dibenz(b,f)azepine [Iminodibenzyl, 494-19-9] as raw material was acylated by triphosgene, after bromination by bromine and dehydrobromination, reacted with sodium hydroxide in isopropanol to give Iminostilbene. | | Definition | ChEBI: Iminostilbene is a mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. It has a role as a marine xenobiotic metabolite. It is a mancude organic heterotricyclic parent and a dibenzoazepine. | | General Description | 5H-Dibenz[b,f]azepine, a tricyclic amine with a seven-membered ring, is commonly known as iminostilbene. It is used as an intermediate or a starting material in the synthesis of many anticonvulsant drugs.It is also used as a starting material to prepare pharmacologically important dibenzoazepine-pyridazine derivatives and synthesize olefinic multidentate ligand, which is used to prepare Rh(I) complexes. | | Biochem/physiol Actions | 2-(Bromomethyl)naphthalene is a fluorescent alkyl bromide. It causes the esterification of free carboxyl groups formed at the surface of polyethylene terephthalate by enzyme hydrolysis. It acts as organic electrophile in the P4S10/acyloin reaction. |
| Iminostilbene Preparation Products And Raw materials |
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