Other grades of this product :
| Ropinirole Basic information |
| Ropinirole Chemical Properties |
| Melting point | 243-250°C | | Boiling point | 410.5±45.0 °C(Predicted) | | density | 1.040±0.06 g/cm3(Predicted) | | pka | 14.17±0.20(Predicted) | | CAS DataBase Reference | 91374-21-9(CAS DataBase Reference) |
| Ropinirole Usage And Synthesis |
| Uses | Antiparkinsonian (D2receptor agonist). | | Brand name | Requip (GlaxoSmithKline). | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028 | | Clinical Use | Anti-Parkinson agent
Restless legs syndrome (RLS) | | Drug interactions | Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian
effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian
effect - avoid.
Oestrogens: concentration increased. | | Metabolism | Ropinirole is hepatically metabolised by the cytochrome
P450 enzyme, CYP1A2, and excreted in the urine as
inactive metabolites. |
| Ropinirole Preparation Products And Raw materials |
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