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| 2,2-Dimethoxypropane Basic information |
| 2,2-Dimethoxypropane Chemical Properties |
| Melting point | -47 °C | | Boiling point | 83 °C (lit.) | | density | 0.847 g/mL at 25 °C (lit.) | | vapor density | 3.59 (vs air) | | vapor pressure | 60 mm Hg ( 15.8 °C) | | refractive index | n20/D 1.378(lit.) | | Fp | 12 °F | | storage temp. | Store below +30°C. | | solubility | 180g/l | | form | Liquid | | Specific Gravity | 0.852 (20/4℃) | | color | Clear colorless | | explosive limit | 31%, 58°F | | Water Solubility | 18 g/100 mL (25 ºC) | | BRN | 635678 | | Stability: | Stable. Highly flammable - note low flash point. Vapour may form an explosive mixture with air. May form explosive peroxides when exposed to air. Incompatible with strong oxidizing agents. | | InChIKey | HEWZVZIVELJPQZ-UHFFFAOYSA-N | | CAS DataBase Reference | 77-76-9(CAS DataBase Reference) | | NIST Chemistry Reference | 2,2-Dimethoxypropane(77-76-9) | | EPA Substance Registry System | Propane, 2,2-dimethoxy- (77-76-9) |
| Hazard Codes | F,Xi | | Risk Statements | 11-36-36/37/38 | | Safety Statements | 26-9-37/39-33-16-33,37/39 | | RIDADR | UN 1993 3/PG 2 | | WGK Germany | 2 | | F | 10-21 | | TSCA | Yes | | HazardClass | 3 | | PackingGroup | II | | HS Code | 29110000 | | Toxicity | LD50 orally in Rabbit: > 2260 mg/kg LD50 dermal Rat > 2100 mg/kg |
| 2,2-Dimethoxypropane Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | 2,2-Dimethoxypropane(DMP) is used in histology and considered to be more efficient than ethanol for the dehydration of animal tissue.
| | Uses | 2,2-Dimethoxypropane acts as a dehydrating agent. It also serves as an intermediate in the synthesis of vitamin E, vitamin A and various carotenoids such as astaxanthin. It is used as a reagent for the preparation of 1,2-diols, acetonides, isopropylidene derivatives of sugars, nucleosides, methyl esters of amino acids and enol ethers. | | General Description | 2,2-Dimethoxypropane is an organic compound, which may be used as a protecting agent in the process of the synthesis of structurally related alkaloids like narciclasine and lycoricidine using phenylbromide as the starting material. |
| 2,2-Dimethoxypropane Preparation Products And Raw materials |
| Raw materials | 2,2-DIMETHYL-1,3-DIOXOLANE-->Trimethoxymethane-->Allyl phenyl ether-->Acetone-->Propyne | | Preparation Products | Doxifluridine-->SUCCINAMIC ACID-->L-Glutamic acid dimethyl ester hydrochloride-->[1,3]Dioxepino[5,6-c]pyridin-9-ol, 1,5-dihydro-3,3,8-trimethyl--->Propane, 2-methoxy-2-(1-methylethoxy)--->1-ETHOXY-1-METHOXYPROPANE-->trans-4-Hydroxy-L-proline methyl ester hydrochloride-->Tetramethyl orthosilicate-->1,3-Dioxan-5-ol, 2,2-dimethyl--->Methyl isopropyl ether-->Ethyl 3,4-O-isopropylideneshikiMate |
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