2-Methoxy-4-methylphenol
2-Methoxy-4-methylphenol
  • CAS No.:93-51-6
Other grades of this product :
2-Methoxy-4-methylphenol Basic information
Product Name:2-Methoxy-4-methylphenol
Synonyms:4-hydroxy-3-methoxy-1-methyl-benzene;4-HYDROXY-3-METHOXYTOLUENE;4-METHYLCATECHOL 2-METHYL ETHER;4-METHYLGUAIACOL;4-METHYLGUAJACOL;1-HYDROXY-2-METHOXY-4-METHYLBENZENE;2-2-Methoxy-4-methylphenol;2-Methoxy-4-methylphenol≥ 99% (GC)
CAS:93-51-6
MF:C8H10O2
MW:138.16
EINECS:202-252-9
Product Categories:Pyridines ,Halogenated Heterocycles;Pharmaceutical Raw Materials;API intermediates;bc0001
Mol File:93-51-6.mol
2-Methoxy-4-methylphenol Chemical Properties
Melting point 5 °C (lit.)
Boiling point 221-222 °C (lit.)
density 1.092 g/mL at 25 °C (lit.)
refractive index n20/D 1.537(lit.)
FEMA 2671 | 2-METHOXY-4-METHYLPHENOL
Fp 211 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
pka10.27±0.18(Predicted)
form Liquid
color colorless to light yellow
Specific Gravity1.091.092
Water Solubility Slightly soluble in water.
JECFA Number715
Merck 14,2571
BRN 1862340
CAS DataBase Reference93-51-6(CAS DataBase Reference)
NIST Chemistry ReferencePhenol, 2-methoxy-4-methyl-(93-51-6)
EPA Substance Registry SystemPhenol, 2-methoxy-4-methyl- (93-51-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-24/25
RIDADR 2810
WGK Germany 3
RTECS GP1755000
10
TSCA Yes
HazardClass 6.1(a)
PackingGroup II
HS Code 29095090
MSDS Information
ProviderLanguage
4-Hydroxy-3-methoxy-1-methyl-benzene English
ACROS English
SigmaAldrich English
ALFA English
2-Methoxy-4-methylphenol Usage And Synthesis
Description2-Methoxy-4-methylphenol has a characteristic aromatic odor (sweet, spicy, slightly vanilla-like) and a somewhat bitter taste (vanilla-like). May be prepared by methylation of homopyrocatechin using dimethyl sulfate and alkali; also by hydrogenation of vanillin.
Chemical Properties2-Methoxy-4-methylphenol has a characteristic aromatic odor (sweet, spicy, slightly vanilla-like) and a somewhat bitter taste (vanilla-like).
Chemical PropertiesClear colorless to slightly yellow liquid
OccurrenceOccurs in beechwood tar; also identified in the essential oils of ylang-ylang, jasmine and anise seeds; it is one of the active constituents of creosote. Reported found in Gruyere cheese, smoked fish, cured pork, beer, rum, bourbon whiskey, malt and Scotch whiskey, sherry, white and red wine, cocoa, coffee, tea, mushrooms, mango, pear brandy, malt, wort, dried bonito, Bourbon vanilla, cuttlefish and green maté.
Uses2-Methoxy-4-methylphenol is used in preparation of renewable bis(cyanate) esters.
Uses2-Methoxy-4-methylphenol is used for blending baking and smoked food flavors.
PreparationBy methylation of homopyrocatechin using dimethyl sulfate and alkali; also by hydrogenation of vanillin.
Aroma threshold valuesDetection: 90 ppb. Aroma characteristics at 1.0%: smoky, sweet, phenolic, vanilla, spicy clove with a floral carnation nuance.
Taste threshold valuesTaste characteristics at 1.0 to 1.25 ppm: sweet phenolic, spice, vanilla, medicinal, clove-like, smoky, guaia col-like with a woody, phenolic nuance.
General Description2-Methoxy-4-methylphenol is the major component of black-ripe table olive aroma. It is the major anti-inflammatory compound in bamboo vinegar. Kinetics of reaction of 2-methoxy-4-methylphenol with chlorine atoms was studied.
Biochem/physiol ActionsOdor at 1.0%

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