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| 2-Benzoylpyridine Basic information |
| Product Name: | 2-Benzoylpyridine | | Synonyms: | ketone,phenyl2-pyridyl;Phenyl(2-pyridinyl)methanone;phenyl-2-pyridinyl-methanon;Pyridine, 2-benzoyl-;AKOS B022444;AKOS 94378;2-BENZOYLPYRIDINE;PHENYL(PYRIDIN-2-YL)METHANONE | | CAS: | 91-02-1 | | MF: | C12H9NO | | MW: | 183.21 | | EINECS: | 202-034-3 | | Product Categories: | Pyridines derivates | | Mol File: | 91-02-1.mol |
| 2-Benzoylpyridine Chemical Properties |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | OB6400000 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29333999 |
| 2-Benzoylpyridine Usage And Synthesis |
| Chemical Properties | COLOURLESS TO SLIGHTLY YELLOW CRYSTALLINE CHUNKS | | Uses | Organic synthesis. | | Uses | 2-Benzoylpyridine is used as a reagent to assist crosslinking in acrylic coating compounds in the polymers industry. 2-Benzoylpyridine is also a precursor for thioemicarbazone compounds that exhibit high cytotoxic activity against human leukemia cell lines and also posesses some antiinflammatory qualities. | | Synthesis Reference(s) | Journal of Heterocyclic Chemistry, 24, p. 1061, 1987 DOI: 10.1002/jhet.5570240429Tetrahedron Letters, 25, p. 1715, 1984 DOI: 10.1016/S0040-4039(01)81152-7 | | Purification Methods | Dissolve 2-benzoylpyridine in Et2O, shake it with aqueous NaHCO3, H2O, dry it over MgSO4 and evaporate. The residue solidifies on cooling. The solid can be recrystallised from pet ether. Its hydrochloride crystallises from Me2CO, m 126-127o, and the 2,4-dinitrophenylhydrazone has m 193-195o. It distils at high vacuum. [Kinkerton & Thames J Organomet Chem 24 623 1970, Beilstein 21/8 V 566.] |
| 2-Benzoylpyridine Preparation Products And Raw materials |
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