Tropisetron hydrochloride

Tropisetron hydrochloride
  • CAS No.:105826-92-4
Other grades of this product :
Tropisetron hydrochloride Basic information
Product Name:Tropisetron hydrochloride
Synonyms:3-TROPANYLINDOLE-3-CARBOXYLATE HYDROCHLORIDE;(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLIC ACID ESTER MONOHYDROCHLORIDE;TROPISETRON HYDROCHLORIDE 98.5-101.5%;TropisetronHcl/Mesylate;1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1);1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrochloride;Novaban;SDZ-ICS 930
CAS:105826-92-4
MF:C17H21ClN2O2
MW:320.81
EINECS:630-417-9
Product Categories:Serotonin;Serotonin receptor;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;NAVOBAN;Antiemetic;zjh
Mol File:105826-92-4.mol
Tropisetron hydrochloride Chemical Properties
Melting point 283-285°C
RTECS NL6012520
storage temp. 2-8°C
solubility H2O: >10mg/mL
form solid
color White to Light yellow
Water Solubility Soluble in water
Merck 14,9783
CAS DataBase Reference105826-92-4(CAS DataBase Reference)
Safety Information
RIDADR 2811
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 29399990
MSDS Information
Tropisetron hydrochloride Usage And Synthesis
Chemical PropertiesWhite to Off-White Crystalline Solid
UsesSpecific serotonin (5-HT3) receptor antagonist. Antiemetic.
UsesA selective 5-HT3 serotonin receptor antagonist
DefinitionChEBI: A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Biological ActivityPotent, orally active 5-HT 3 receptor antagonist. Antiemetic.
Biochem/physiol ActionsTropisetron a selective serotonin 5-HT3 receptor antagonist is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy . In the treatment of fibromyalgia syndrome (FMS) tropisetron reduced not only pain perception but also had a favourable effect on cardiac dysfunction during treatment.
Tropisetron hydrochloride Preparation Products And Raw materials

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