Other grades of this product :
| 4-Biphenylacetic acid Basic information |
| 4-Biphenylacetic acid Chemical Properties |
| Melting point | 159-160 °C (lit.) | | Boiling point | 312.08°C (rough estimate) | | density | 1.1035 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO: soluble50mg/mL, clear, colorless to yellow | | form | Powder | | pka | 4.29±0.10(Predicted) | | color | Beige | | Water Solubility | 39.27mg/L(25 ºC) | | Merck | 14,3316 | | BRN | 1211592 | | InChIKey | QRZAKQDHEVVFRX-UHFFFAOYSA-N | | CAS DataBase Reference | 5728-52-9(CAS DataBase Reference) |
| 4-Biphenylacetic acid Usage And Synthesis |
| Description | Felbinac Is the active metabolite of the non-steroidal antiinflammatory agent,
fenbufen. Applied topically as a gel to joints, it is useful in the symptomatic relief
of articular inflammation and pain. | | Chemical Properties | Off-white powder | | Originator | Lederle (USA) | | Uses | Anti-inflammatory, analgesic drug. | | Uses | 4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug. | | Brand name | Dolinac (Wyeth-Ayerst); Flexfree(Wyeth-Ayerst); Napageln (Wyeth-Ayerst); Target
(Wyeth-Ayerst); Traxam (Wyeth-Ayerst). | | General Description | 4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors. | | Safety Profile | Poison by subcutaneous route.Moderately toxic by ingestion and intraperitoneal routes.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits acrid smoke and fumes. |
| 4-Biphenylacetic acid Preparation Products And Raw materials |
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