Tegaserod

Tegaserod
  • CAS No.:145158-71-0
Other grades of this product :
Tegaserod Basic information
Product Name:Tegaserod
Synonyms:TEGASEROD;2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide;Tegaserode;Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-;Tegaserod USP/EP/BP;Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3;Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10;Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
CAS:145158-71-0
MF:C16H23N5O
MW:301.39
EINECS:
Product Categories:
Mol File:145158-71-0.mol
Tegaserod Chemical Properties
Melting point 155°
Boiling point 470.6±48.0 °C(Predicted)
density 1.18
storage temp. 2-8°C
pka15.81±0.30(Predicted)
CAS DataBase Reference145158-71-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 36/37-36-26
MSDS Information
Tegaserod Usage And Synthesis
UsesTreatment of gastrointestinal motility disorders (selective serotonin 5HT4antagonist).
IndicationsTegaserod (Zelnorm) is serotonin-4 (5-HT4) receptor agonists that stimulate GI motility.
Brand nameZelmac (Novartis).
Clinical UseTegaserod is being developed as a treatment for constipation- predominant irritable bowel syndrome (IBS). Within the first week, patients treated with tegaserod had significant improvements in abdominal pain and discomfort, constipation, and overall well-being. Efficacy was maintained throughout the treatment period. Tegaserod also demonstrated significant improvements in the three bowel-related assessments (stool frequency, stool consistency, and straining) within the first week, and these improvements were sustained throughout the treatment period. The most common adverse events reported thus far are headache and diarrhea.
Tegaserod Preparation Products And Raw materials

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