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5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

CAS No.：239463-85-5

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5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Basic information

Product Name:	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate
Synonyms:	5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate (1:1);R)-5-(2-aMinopropyl)-1-(3-benzyloxypropyl) indoline-7-carbonitrile tartrate;(R)-3-(5-(2-aMinopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate;5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate;5-[(2R)-2-AMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioa;5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole(2R,3R)-2,3-dihydroxybutanedioat;5-((2R)-2-AMINOPROPLY)-1-(3-(BENZYLOXY)PROPYL)-2,3-DIHYDRO-7-CARBONOTRILE-1H-INDOLE-(2R,3R)-2,3-DIHYDROBUTANEDIOATE (ACI;5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile -1H-indole (2R,3R)-2,3-dihydroxybutanedioate
CAS:	239463-85-5
MF:	C26H31N3O8
MW:	513.55
EINECS:	688-292-1
Product Categories:	Intermediates
Mol File:	239463-85-5.mol

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Chemical Properties

Melting point	> 180° C (dec.)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli
form	Solid
color	Off-White to Pale Yellow
Stability:	Hygroscopic
CAS DataBase Reference	239463-85-5

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MSDS Information

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Usage And Synthesis

Uses	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-Dihydroxybutanedioate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy.

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Preparation Products And Raw materials

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