1-Methyl-1H-indole-3-carboxylic acid

1-Methyl-1H-indole-3-carboxylic acid
  • CAS No.:32387-21-6
Other grades of this product :
1-Methyl-1H-indole-3-carboxylic acid Basic information
Product Name:1-Methyl-1H-indole-3-carboxylic acid
Synonyms:1-Methylindole-3-carboxylic acid ,97%;N-Methylindole acetate;1H-Indole-3-carboxylic acid, 1-Methyl-;Methylindole-3-carboxylic;Ramosetron Impurity 7;1-METHYL-3-INDOLECARBOXYLIC ACID;1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID;1-METHYLINDOLE-3-CARBOXYLIC ACID
CAS:32387-21-6
MF:C10H9NO2
MW:175.18
EINECS:
Product Categories:Heterocycle-Indole series;Heterocyclic Compounds;Acids and Derivatives;Building Blocks;Heterocyclic Building Blocks;Indoles;Heterocycles;Indole
Mol File:32387-21-6.mol
1-Methyl-1H-indole-3-carboxylic acid Chemical Properties
Melting point 197-200 °C (dec.) (lit.)
Boiling point 389.0±15.0 °C(Predicted)
density 1.24±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka4.01±0.10(Predicted)
form Crystalline Powder
color White to beige
CAS DataBase Reference32387-21-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
1-Methyl-1H-indole-3-carboxylic acid Usage And Synthesis
Chemical PropertiesOff-white solid
Uses
  • Reactant for preparation of bisindolyl pyrimidinones analogs of PKC inhibitor LY333531
  • Reactant for preparation of (heteroaryl)(carboxamido)arylpyrrole derivatives as Cdc7 kinase inhibitors, antitumor and antiproliferative agents
  • Reactant for preparation of (pyrrolidinylmethoxy)cyclohexanecarboxylic acids as antigen-4 (VLA-4) antagonists
  • Reactant for preparation of EphB3 receptor tyrosine kinase inhibitors
  • Reactant for preparation of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
  • Reactant for preparation of potent nonpeptidic urotensin II receptor agonists
  • Reactant for preparation of pyrrolizidine esters, amides, and ureas as 5-HT4 receptor ligands
General Description1-Methylindole-3-carboxylic acid is an indole derivative that can be prepared by the oxidation of 1-methylindole-3-aldehyde with alkaline potassium permanganate.

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