D-DOPA

D-DOPA
  • CAS No.:5796-17-8
Other grades of this product :
D-DOPA Basic information
Product Name:D-DOPA
Synonyms:D-3-(3,4-Dihydroxyphenyl)alanine;D-Tyrosine,3-hydroxy-;H-D-TYR(3-HYDROXY)-OH;H-D-PHE(3,4-DI-HYDROXY)-OH;D-3-HYDROXYTYROSINE;D-BETA-(3,4-DIHYDROXYPHENYL)ALANINE;D-3,4-DIHYDROXYPHENYLALANINE;D-DOPA
CAS:5796-17-8
MF:C9H11NO4
MW:197.19
EINECS:227-343-0
Product Categories:Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Chiral Reagents;Neurochemicals
Mol File:5796-17-8.mol
D-DOPA Chemical Properties
Melting point 276-278 °C(lit.)
alpha D11 +13.0° (c = 5.27 in 1N HCl)
Boiling point 448.4±45.0 °C(Predicted)
density 1.468±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility 0.5 M HCl: soluble
form powder
pka2.24±0.20(Predicted)
color white to tan
Merck 13,3454
BRN 2417637
CAS DataBase Reference5796-17-8(CAS DataBase Reference)
Safety Information
WGK Germany 3
10-23
HS Code 2922500090
MSDS Information
ProviderLanguage
SigmaAldrich English
D-DOPA Usage And Synthesis
Chemical PropertiesTan Solid
UsesA DOPA enantiomer that lacks biological activity.
UsesD-DOPA (Levodopa EP Impurity D) is a DOPA enantiomer that lacks biological activity.
DefinitionChEBI: The D-enantiomer of dopa.
Biochem/physiol ActionsDOPA enantiomer that lacks biological activity.
Purification MethodsLikely impurities are vanillin, hippuric acid, 3-methoxytyrosine and 3-aminotyrosine. DOPA recrystallises from large volumes of H2O forming colourless white needles; its solubility in H2O is 0.165%, but it is insoluble in EtOH, *C6H6, CHCl3, and EtOAc. Also crystallise it by dissolving it in dilute HCl and adding dilute ammonia to give pH 5, under N2. Alternatively, crystallise it from dilute aqueous EtOH. It is rapidly oxidised in air when moist, and darkens, particularly in alkaline solution. Dry it in vacuo at 70o in the dark, and store it in a dark container preferably under N2. It has at 220.5nm (log 3.79) and 280nm (log 3.42) in 0.001N max HCl. [Yamada et al. Chem Pharm Bull Jpn 10 693 1962, Bretschneider et al. Helv Chim Acta 56 2857 1973, NMR: Jardetzky & Jardetzky J Biol Chem 233 383 1958, Beilstein 4 IV 2492, 2493.]
D-DOPA Preparation Products And Raw materials

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