Probenazole

Probenazole
  • CAS No.:27605-76-1
Other grades of this product :
Probenazole Basic information
Product Name:Probenazole
Synonyms:3-(allyloxy)-1,2-benzisothiazole1,1-dioxide;oryzaemate;po-20;probenazole (jmaf);ORYZAMATE;PROBENAZOIE;3-Allyloxy-1,2-benzoisothiazole 1,1-dioxide;Probenazole Standard
CAS:27605-76-1
MF:C10H9NO3S
MW:223.25
EINECS:
Product Categories:
Mol File:27605-76-1.mol
Probenazole Chemical Properties
Melting point 136~141℃
Boiling point 220°C (rough estimate)
density 1.3588 (rough estimate)
vapor pressure 5 x 10-4 Pa (20 °C) (est.)
refractive index 1.6500 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
Water Solubility 150 mg l-1
pka-2.43±0.20(Predicted)
color White to Off-White
CAS DataBase Reference27605-76-1(CAS DataBase Reference)
NIST Chemistry ReferenceProbenazole(27605-76-1)
Safety Information
HS Code 29342000
MSDS Information
Probenazole Usage And Synthesis
UsesProbenazole is used for the control of rice blast and bacterial diseases in paddy rice.
UsesProbenazole can be used in agricultural use and biological study of preparation of nicotinamide compounds containing chiral oxazoline and application thereof as agricultural antimicrobial agent.
DefinitionChEBI: A member of the class of 1,2-benzothiazoles that is 1,2-benzothiazole 1,1-dioxide substituted at position 3 by an allyloxy group. A fungicide used to control rice blast.
Metabolic pathwayProbenazole is metabolised readily in plants by hydrolytic ring opening followed by a cyclisation-induced dealkylation to form saccharin which is N-glucosylated. Saccharin may be the active metabolite of probenazole. No information on the fate of probenazole in soil or animals could be located.
MetabolismProbenazole is taken up by the rice plants after spray or paddy application and distributed throughout the plants as parent compound or as one of its metabolites . The main metabolites of probenazole in rice are 2-sulfamoyl-allyl-benzoate, saccharin, and N-β- D-glucopyranosylsaccharin (37).
DegradationProbenazole is a stable compound but it is subject to hydrolysis.

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