5-Amino-2-chloropyridine
5-Amino-2-chloropyridine
  • CAS No.:5350-93-6
Other grades of this product :
5-Amino-2-chloropyridine Basic information
Product Name:5-Amino-2-chloropyridine
Synonyms:3-PYRIDINAMINE, 6-CHLORO-;3-AMINO-6-CHLOROPYRIDINE;6-CHLOROPYRIDIN-3-AMINE;6-CHLORO-PYRIDIN-3-YLAMINE;5-AMINO-2-CHLOROPYRIDINE;2-CHLORO-5-AMINOPYRIDINE;TIMTEC-BB SBB004234;AMINO CHLOROPYRIDINE
CAS:5350-93-6
MF:C5H5ClN2
MW:128.56
EINECS:226-322-3
Product Categories:Chloropyridines;Halopyridines;Boronic Acid;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PYRIDINE;Amines;blocks;Pyridines;pyridine derivative;Pyridine Series;Pyridines derivates;Amino-pyridine series;compounds of pyridine;bc0001
Mol File:5350-93-6.mol
5-Amino-2-chloropyridine Chemical Properties
Melting point 81-83 °C(lit.)
Boiling point 205.39°C (rough estimate)
density 1.2417 (rough estimate)
refractive index 1.5110 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka1.94±0.10(Predicted)
form powder to crystal
color White to Brown
BRN 108891
InChIKeyQAJYCQZQLVENRZ-UHFFFAOYSA-N
CAS DataBase Reference5350-93-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29333999
MSDS Information
ProviderLanguage
5-Amino-2-chloropyridine English
SigmaAldrich English
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ALFA English
5-Amino-2-chloropyridine Usage And Synthesis
Chemical PropertiesLight yellow to brown crystalline powder
Uses5-Amino-2-chloropyridine was used in the synthesis of [2H5]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals.
General Description5-Amino-2-chloropyridine undergoes Suzuki-Miyaura coupling with sterically hindered 2,6-dimethylphenylboronic acid. It undergoes facile temperature dependent displacement of chloride by bromide via Sandmeyer reaction to yield 2,5-dibromopyridine.

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