| Cefuroxime 1-acetoxyethyl ester Basic information |
| Product Name: | Cefuroxime 1-acetoxyethyl ester |
| Synonyms: | 1-(acetyloxy)ethylest;cxm-ax;(6R-(6alpha,7beta(Z)))-3-(((Aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester;Cefuroxime 1-acetoxyethyl ester;[6R-[6α，7β(Z)]]-3-[(Aminocarbonyloxy)methyl]-7-[2-(furan-2-y1)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-car-boxylic acid(2-acetoxy)ethylester;Elobact：Oraxim;Maxitil;(6R)-3-[[(Aminocarbonyl)oxy]methyl]-7α-[[2-furanyl[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-acetoxyethyl ester |
| CAS: | 64544-07-6 |
| MF: | C20H22N4O10S |
| MW: | 510.47 |
| EINECS: | 638-760-6 |
| Product Categories: | Pharmaceutical intermediates;Pharmaceutical intermediate;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;VIROPTIC;Pharmaceuticals;Sulfur & Selenium Compounds |
| Mol File: | 64544-07-6.mol |
| Cefuroxime 1-acetoxyethyl ester Chemical Properties |
| Melting point | 175-180 °C |
| Boiling point | 250°C (rough estimate) |
| density | 1.3927 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: soluble1mg/mL |
| form | powder |
| pka | 8.31±0.60(Predicted) |
| color | white to off-white |
| InChIKey | KEJCWVGMRLCZQQ-UXXYIVIXSA-N |
| CAS DataBase Reference | 64544-07-6(CAS DataBase Reference) |
| Safety Information |
| WGK Germany | 2 |
| HS Code | 2941906000 |
| Hazardous Substances Data | 64544-07-6(Hazardous Substances Data) |
| Toxicity | LD50 oral in rabbit: 200mg/kg |
| MSDS Information |
| Cefuroxime 1-acetoxyethyl ester Usage And Synthesis |
| Chemical Properties | White to Off-White Solid |
| Uses | Cefuroxime 1-acetoxyethyl ester is an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. |
| Uses | It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial. |
| Uses | antiviral (opthalmic) |
| Cefuroxime 1-acetoxyethyl ester Preparation Products And Raw materials |
| Raw materials | Cefuroxime-->(E)-CefuroxiMe Axetil DISCONTINUED-->1-Bromoethyl acetate |
| Preparation Products | Diisopropyl ether |
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