Other grades of this product :
| THIP HYDROCHLORIDE Basic information |
| Product Name: | THIP HYDROCHLORIDE | | Synonyms: | THIP HYDROCHLORIDE;4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3(2h)-onehydrate;4-c)pyridin-3(2h)-one,4,5,6,7-tetrahydro-isoxazolo(hydrate;gaboxadol;4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL;4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HYDROCHLORIDE;4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one;THIP | | CAS: | 64603-91-4 | | MF: | C6H8N2O2 | | MW: | 140.14 | | EINECS: | 264-963-0 | | Product Categories: | GABA/Glycine receptor | | Mol File: | 64603-91-4.mol |
| THIP HYDROCHLORIDE Chemical Properties |
| Melting point | 242-244° (dec) | | density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | ethanol: 0.91 mg/mL | | pka | pKa (water, 25°): 4.44 ±0.03; 8.48 ±0.04 | | form | solid | | color | white | | Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | NY3396800 |
| THIP HYDROCHLORIDE Usage And Synthesis |
| Description | Gaboxadol HCl (64603-91-4) is a GABA-A receptor agonist. Hypnotic agent. | | Uses | GABAa agonist, GABAc antagonist | | Biological Activity | Systemically active GABA A receptor agonist and GABA C receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats. | | References | 1) Meera et al. (2011), Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors; J. Neurophysiol., 106 2057 |
| THIP HYDROCHLORIDE Preparation Products And Raw materials |
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