INDOLE-3-GLYOXYLYL CHLORIDE

INDOLE-3-GLYOXYLYL CHLORIDE
  • CAS No.:22980-09-2
Other grades of this product :
INDOLE-3-GLYOXYLYL CHLORIDE Basic information
Product Name:INDOLE-3-GLYOXYLYL CHLORIDE
Synonyms:3-INDOLYLGLYOXALYL CHLORIDE;3-INDOLYL-GLYOXYL CHLORIDE;3-INDOLEGLYOXYLYL CHLORIDE;ALPHA-OXO-INDOLE-3-ACETYL CHLORIDE;INDOLE-3-GLYOXYLOYL CHLORIDE;INDOLE-3-GLYOXYLYL CHLORIDE;(2-(3-INDOLYL)-2-OXOACETYL) CHLORIDE;alpha-Oxoindoleacetyl chloride
CAS:22980-09-2
MF:C10H6ClNO2
MW:207.61
EINECS:245-362-2
Product Categories:Aromtatics, Heterocycles, Indole Derivatives, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Building Blocks;Aromtatics;C10;Chemical Synthesis;Heterocyclic Building Blocks;Building Blocks;Heterocyclic Building Blocks;Indoles;Heterocycles;Impurities;Indole Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocyclic Compounds
Mol File:22980-09-2.mol
INDOLE-3-GLYOXYLYL CHLORIDE Chemical Properties
Melting point 138 °C (dec.) (lit.)
Boiling point 413.9±37.0 °C(Predicted)
density 1.463±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka14.29±0.30(Predicted)
Sensitive Moisture Sensitive
BRN 147693
CAS DataBase Reference22980-09-2(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-27-36/37/39-45
RIDADR UN 1759 8/PG 2
WGK Germany 3
HazardClass 8
PackingGroup II
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
INDOLE-3-GLYOXYLYL CHLORIDE Usage And Synthesis
UsesINDOLE-3-GLYOXYLYL CHLORIDE is an indole derivative used in the preparation of reagents for chemiluminescent enzyme immunoassay. It is an impurity in the manufacture of tryptamines and related compounds.
Uses• ;Reactant for preparation of dual IGF-1R/SRC inhibitors1• ;Reactant for preparation of indolylglyoxylamides as a new class of antileishmanial agents2• ;Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents3• ;Reactant for diastereoselective synthesis of heptacyclic core of dragmacidin E4• ;Reactant for preparation of benzoylmethylpyrrolopyridinylethanedione as HIV-1 inhibitor5• ;Reactant for preparation of fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D16
Uses
  • Reactant for preparation of dual IGF-1R/SRC inhibitors
  • Reactant for preparation of indolylglyoxylamides as a new class of antileishmanial agents
  • Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents
  • Reactant for diastereoselective synthesis of heptacyclic core of dragmacidin E
  • Reactant for preparation of benzoylmethylpyrrolopyridinylethanedione as HIV-1 inhibitor
  • Reactant for preparation of fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1
INDOLE-3-GLYOXYLYL CHLORIDE Preparation Products And Raw materials
Preparation ProductsTryptophol-->Methyl indolyl-3-glyoxylate

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