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| 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Basic information |
| Product Name: | 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one | | Synonyms: | 1,2,4-TRIAZOLO-[4,3-A]PYRIDINE-3(2H)-ONE;1,2,4-TRIAZOLE(4,3)PYRIDIN-3-(2H)-ONE;1,2,4-TRIAZOL-(4,3-A)-PYRIDINE 3 (2H)-ONE;1,2,4-Triazolopyridin-3-one;3-HYDROXYTRIAZOLO[4,3-A]PYRIDINE;3-HYDROXY-1,2,4-TRIAZOLO[4,3-A]PYRIDINE;1,2,4-Triazole-(4,3-alpha)pyri;Trazodone Impurity 15 | | CAS: | 6969-71-7 | | MF: | C6H5N3O | | MW: | 135.12 | | EINECS: | 230-191-8 | | Product Categories: | Heterocycles;intermediate for some organic synthesis;APIs & Intermediate;Pyrimidine;Pyridines;Fused Ring Systems | | Mol File: | 6969-71-7.mol |
| 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Chemical Properties |
| Melting point | 231°C | | density | 1.51±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | pka | 7.86±0.20(Predicted) | | form | Solid | | color | Light Brown to Brown | | BRN | 607433 | | Stability: | Light Sensitive | | InChIKey | LJRXNXBFJXXRNQ-UHFFFAOYSA-N | | LogP | 0.113 | | CAS DataBase Reference | 6969-71-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29339900 |
| Provider | Language |
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ALFA
| English |
| 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Usage And Synthesis |
| Chemical Properties | Beige Solid | | Uses | 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one was used to prepare a congener of Trazodone (T718500) which was found to be a potent and selective inhibitor of synaptosomal uptake of 5-hydroxytryptamine. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 28, p. 1394, 1985 DOI: 10.1021/jm00148a004 |
| 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Preparation Products And Raw materials |
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![1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one](/img/6969-71-7.jpg "1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one")
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