Other grades of this product :
| 5-Aminoindole Basic information |
| 5-Aminoindole Chemical Properties |
| Melting point | 131-133 °C (dec.) (lit.) | | Boiling point | 190 °C / 6mmHg | | density | 1.1083 (rough estimate) | | refractive index | 1.6013 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO, Methanol | | pka | 17.39±0.30(Predicted) | | form | Crystalline Powder | | color | Off-white to gray-brown | | Water Solubility | insoluble | | Sensitive | Air & Light Sensitive | | BRN | 112348 | | InChIKey | ZCBIFHNDZBSCEP-UHFFFAOYSA-N | | CAS DataBase Reference | 5192-03-0(CAS DataBase Reference) | | NIST Chemistry Reference | 5-Aminoindole(5192-03-0) | | EPA Substance Registry System | 5-Aminoindole (5192-03-0) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38-68 | | Safety Statements | 26-45-36/37 | | WGK Germany | 3 | | F | 10 | | Hazard Note | Irritant | | TSCA | Yes | | HazardClass | AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD | | HS Code | 29339990 |
| 5-Aminoindole Usage And Synthesis |
| Chemical Properties | Grey Crystals | | Uses | Reactant for preparation of:- Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
- Cytotoxic and antimitotic agents
- Insulin-like growth factor 1 receptor inhibitors
- Antitumoral agents
- Factor Xa inhibitor
- Potential antivascular agents
- Gli1-mediated transcription in the Hedgehog pathway
- Inhibitors of receptor tyrosine kinase with antiangiogenic effects
- PKCθ inhibitors
- HIV protease inhibitors
| | Uses | 5-Aminoindole functions as a ligand for hydrophobic charge induction chromatography. A reagent for synthetic elaboration. | | Definition | ChEBI: An indolamine carrying an amino group at position 5. |
| 5-Aminoindole Preparation Products And Raw materials |
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