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| Guanosine-5'-diphosphate disodium salt Basic information | | Uses |
| Guanosine-5'-diphosphate disodium salt Chemical Properties |
| Melting point | >280°C (dec.) | | storage temp. | -20°C | | solubility | H2O: 50 mg/mL, clear, colorless | | form | Powder | | color | White | | Water Solubility | Soluble in water | | Stability: | Hygroscopic |
| Guanosine-5'-diphosphate disodium salt Usage And Synthesis |
| Uses | Guanosine 5'-diphosphate disodium salt is a useful research chemical. | | Uses | Guanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors. | | General Description | Guanosine 5′-diphosphate (GDP) is a purine nucleotide and is interconvertible to guanosine by the action of ectonucleotidases and by nucleoside phosphorylase into guanine. GDP is majorly acted upon by 5′‐ectonucleotidases in neuronal cells. | | Biochem/physiol Actions | Guanosine based nucleosides play a key role in multiple cellular processes and generation growth factors. Elevated levels of guanosine 5′-diphosphate (GDP) is associated with the pathogenesis of neurological disorders. GDP is bound to G protein . G protein coupled receptors (GPCRs) activate G proteins by exchanging the bound GDP to GTP. GDP is potent inhibitor agent of hepcidin- ferroportin complex and may be effective for promoting erythropoiesis and treating anemia of inflammation(AI). |
| Guanosine-5'-diphosphate disodium salt Preparation Products And Raw materials |
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