Guanosine-5'-diphosphate disodium salt

Guanosine-5'-diphosphate disodium salt
  • CAS No.:7415-69-2

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  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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Guanosine-5'-diphosphate disodium salt Basic information
Uses
Product Name:Guanosine-5'-diphosphate disodium salt
Synonyms:GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT;GUANOSINE-5'-DIPHOSPHORIC ACID, DISODIUM;GDP, NA2H;GDP;5'-GDP-Na;guanosine 5-(disodium hydrogen pyrophosphate);GUANOSINE 5'-DIPHOSPHATE DISODIUM SALT 85+%;Guanosine 5-(trihydrogen diphosphate), disodium salt
CAS:7415-69-2
MF:C10H16N5NaO11P2
MW:467.2
EINECS:231-026-2
Product Categories:Material;Pharmaceutical;7415-69-2
Mol File:7415-69-2.mol
Guanosine-5'-diphosphate disodium salt Chemical Properties
Melting point >280°C (dec.)
storage temp. -20°C
solubility H2O: 50 mg/mL, clear, colorless
form Powder
color White
Water Solubility Soluble in water
Stability:Hygroscopic
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36/37/39-27-26
WGK Germany 3
F 3-10-21
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
Guanosine-5'-diphosphate disodium salt Usage And Synthesis
UsesGuanosine 5'-diphosphate disodium salt is a useful research chemical.
UsesGuanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.
General DescriptionGuanosine 5′-diphosphate (GDP) is a purine nucleotide and is interconvertible to guanosine by the action of ectonucleotidases and by nucleoside phosphorylase into guanine. GDP is majorly acted upon by 5′‐ectonucleotidases in neuronal cells.
Biochem/physiol ActionsGuanosine based nucleosides play a key role in multiple cellular processes and generation growth factors. Elevated levels of guanosine 5′-diphosphate (GDP) is associated with the pathogenesis of neurological disorders. GDP is bound to G protein . G protein coupled receptors (GPCRs) activate G proteins by exchanging the bound GDP to GTP. GDP is potent inhibitor agent of hepcidin- ferroportin complex and may be effective for promoting erythropoiesis and treating anemia of inflammation(AI).
Guanosine-5'-diphosphate disodium salt Preparation Products And Raw materials

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