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| 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Basic information |
| Product Name: | 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- | | Synonyms: | 5-Chloro-2-isopropyl-pent-4-enoic acid dimethylamide;(2S,4E)-5-Chloro-N,N-dimethyl-2-(1-methylethyl)-4-pentenamide;4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)-;Aliskiren inter-4;(E)-(S)-5-chloro-2-isopropyl-pent-4-enoic acid dimethylamide;(S,E)-5-chloro-2-isopropyl-N,N-dimethylpent-4-enamide;5-CHLORO-2-ISOPROPYL-N, N-DIMETHYLPENT-4-ENAMIDE;(E)-5-chloro-2-isopropyl-N,N-diMethylpent-4-enaMide | | CAS: | 324519-68-8 | | MF: | C10H18ClNO | | MW: | 203.71 | | EINECS: | | Product Categories: | Drug Intermediates;Aliskiren Intermediate | | Mol File: | 324519-68-8.mol |
| 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Chemical Properties |
| 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Usage And Synthesis |
| Uses | (2S,4E)-5-Chloro-2-isopropyl-N,N-dimethylpent-4-enamide is an intermediate in the preparation of orally active renin inhibitor Aliskiren (A536000). |
| 4-Pentenamide, 5-chloro-N,N-dimethyl-2-(1-methylethyl)-, (2S,4E)- Preparation Products And Raw materials |
| Raw materials | 4-Pentenoic acid, 5-chloro-2-(1-methylethyl)-, methyl ester, (4E)--->(S,E)-ethyl 5-chloro-2-isopropylpent-4-enoate-->(1,3-Dioxane-4,6-dione, 2,2-diMethyl-5-(1-Methylethyl))-->Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester-->2-Isopropylmalonic acid dimethyl ester-->Aliskiren inter-11-->4-Pentenoic acid, 5-chloro-2-(1-methylethyl)-, (2S,4E)--->Dimethylamine-->Dimethylamine hydrochloride |
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