Product

N-Succinimidyl maleimidoacetate

CAS No.：55750-61-3

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N-Succinimidyl maleimidoacetate Basic information

Product Name:	N-Succinimidyl maleimidoacetate
Synonyms:	MALEIMIDOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER;N-SUCCINIMIDYL MALEIMIDOACETATE;a-Maleimidoacetic acid-NHS;N-(α-Maleimidoacetoxy)succinimide Ester(AMAS);1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione;N-(α-MaleiMidoacetoxy)succiMide;1H-Pyrrole-2,5-dione, 1-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-;MaleiMidoacetic
CAS:	55750-61-3
MF:	C10H8N2O6
MW:	252.18
EINECS:
Product Categories:	Nitric Oxide Reagents;Cross Linking Reagents;Maleimide Derivatives;Crosslinking;Heterobifunctional Cross-Linking Reagents;Protein Modification;Cross Linking Reagents,Maleimide Derivatives;MTS & Sulfhydryl Active Reagents
Mol File:	55750-61-3.mol

N-Succinimidyl maleimidoacetate Chemical Properties

Melting point	174-175°C
Boiling point	430.1±47.0 °C(Predicted)
density	1.63±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat
form	Solid
pka	-2.69±0.20(Predicted)
color	White to Off-White
InChIKey	TYKASZBHFXBROF-UHFFFAOYSA-N
CAS DataBase Reference	55750-61-3

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29280000

MSDS Information

Provider	Language
SigmaAldrich	English

N-Succinimidyl maleimidoacetate Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	Maleimidoacetic acid N-hydroxysuccinimide ester is a crosslinking reagent that contains NHS ester- and maleimide-reactive groups at the opposite ends of a 4.4 ? spacer arm. This configuration allows for sequential, two-stage conjugation with amine and sulfhydryl functional groups in the preparation of protein-hapten or protein-protein conjugates.
Uses	A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates.
Uses	A hetero-bifunctional cross-linking reagent for the preparation of protein-protein or protein-hapten conjugates

N-Succinimidyl maleimidoacetate Preparation Products And Raw materials

Raw materials

2-Butenoic acid, 4-[(carboxymethyl)amino]-4-oxo--->1H-Pyrrole-1-acetyl chloride, 2,5-dihydro-2,5-dioxo--->N-Glycinylmaleamic acid-->2-Maleimido acetic acid-->N-Hydroxysuccinimide

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