Other grades of this product :
| SEA-0400 Basic information |
| Product Name: | SEA-0400 | | Synonyms: | SEA-0400;BenzenaMine, 2-[4-[(2,5-difluorophenyl)Methoxy]phenoxy]-5-ethoxy-;2-[4-[(2,5-Difluorophenyl)methoxy]phenoxy]-5-ethoxybenzenamine;SEA 0400; SEA-0400;2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline;2-(4-((2,5-DIFLUOROBENZYL)OXY)PHENOXY)-5-ETHOXYANILINE;CS-1043;SEA 0400; SEA-0400;SEA0400 | | CAS: | 223104-29-8 | | MF: | C21H19F2NO3 | | MW: | 371.38 | | EINECS: | | Product Categories: | | Mol File: | 223104-29-8.mol |
| SEA-0400 Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | insoluble in H2O; ≥18.57 mg/mL in DMSO; ≥46.4 mg/mL in EtOH with ultrasonic | | form | solid |
| SEA-0400 Usage And Synthesis |
| Description | SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger (IC50s = 5, 8.3, and 33 nM for inhibiting Na+-dependent Ca2+ uptake in rat astrocyte, microglia, and cortical neuron cell lines, respectively). It is reported to prevent dopaminergic neurotoxicity in an MPTP mouse model of Parkinson''s disease and to attenuate reperfusion injury in both in vitro and in vivo cerebral ischemic models. | | Uses | SEA 0400 is a novel and selective inhibitor of Na+-Ca2+ exchanger. |
| SEA-0400 Preparation Products And Raw materials |
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