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| 3-Maleimidopropionic acid Basic information |
| 3-Maleimidopropionic acid Chemical Properties |
| Melting point | 103-106 °C (lit.) | | Boiling point | 382.5±25.0 °C(Predicted) | | density | 1.473±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 4.18±0.10(Predicted) | | form | Solid | | color | White | | Water Solubility | Soluble in methanol, dimethyl formamide, alcohol and dimethyl sulfoxide. Slightly soluble in water. | | Sensitive | Moisture Sensitive | | BRN | 1528952 | | InChIKey | IUTPJBLLJJNPAJ-UHFFFAOYSA-N | | CAS DataBase Reference | 7423-55-4(CAS DataBase Reference) |
| 3-Maleimidopropionic acid Usage And Synthesis |
| Description | 3-Maleimidopropionic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Chemical Properties | White to Pale Yellow Solid | | Uses | 3-Maleimidopropionic acid is a sulfhydryl reactive heterobifunctional crosslinking reagent. | | Uses | A sulfhydryl reactive heterobifunctional crosslinking reagent. | | General Description | N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies. |
| 3-Maleimidopropionic acid Preparation Products And Raw materials |
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