Boc-L-Threonine

CAS No.：2592-18-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Boc-L-Threonine Basic information

Product Name:	Boc-L-Threonine
Synonyms:	N-(TERT-BUTOXYCARBONYL)-L-THREONINE 98%;N-T-BOC-L-THREONINE CRYSTALLINE;Boc-L-Threionine;N-ALPHA-T-BUTYLOXYCARBONYL-L-THREONINE;N-Boc-L-threonine, 98+%;BOC-L-THREONINE extrapure;N-(tert-Butoxycarbonyl)-L-threonine, Boc-L-threonine;BOC-L-THREONINE
CAS:	2592-18-9
MF:	C9H17NO5
MW:	219.24
EINECS:	219-987-6
Product Categories:	Threonine [Thr, T];Boc-Amino Acids and Derivative;Amino Acids;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Boc-Amino acid series
Mol File:	2592-18-9.mol

Boc-L-Threonine Chemical Properties

Melting point	80-82 °C(lit.)
Boiling point	360.05°C (rough estimate)
alpha	-8.5 º (c=1, acetic acid)
density	1.2470 (rough estimate)
refractive index	-7 ° (C=1, AcOH)
storage temp.	-20°C
pka	3.60±0.10(Predicted)
form	powder to crystal
color	White to Almost white
optical activity	[α]20/D 8.5±1°, c = 1% in acetic acid
BRN	2331474
CAS DataBase Reference	2592-18-9(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
HS Code	29241990

MSDS Information

Provider	Language
Boc-L-Threonine	English
SigmaAldrich	English
ACROS	English
ALFA	English

Boc-L-Threonine Usage And Synthesis

Chemical Properties

WHITE AMORPHOUS POWDER

Boc-L-Threonine Preparation Products And Raw materials

Raw materials	PLIT-019-->TERT-BUTYL 2,3-DIHYDRO-2-OXO-3-OXAZOLECARBOXYLATE-->Boc-O-Benzyl-L-threonine-->L-THREONINEETHYLESTER-->Carbonofluoridic acid, 1,1-dimethylethyl ester-->Di-tert-butyl dicarbonate-->tert-butyl azidoformate-->2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile-->L-Threonine
Preparation Products	2-Pyridinethione-->2-Hydroxypyridine-->N-BOC-(R)-1-AMINO-2-PROPANOL

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