Erythromycin ethylsuccinate

Erythromycin ethylsuccinate
  • CAS No.:1264-62-6
Other grades of this product :
Erythromycin ethylsuccinate Basic information
Product Name:Erythromycin ethylsuccinate
Synonyms:ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE);ERYTHROMYCIN 2'-(ETHYL SUCCINATE);ERYTHROMYCIN ETHYLSUCCINATE;erythrocinethylsuccinate;erythromycin,mono(ethylsuccinate);erythromycin,mono(ethylsuccinate)(ester);Succinic acid, monoester with erythromycin;Erythromycin 2''-[3-(ethoxycarbonyl)propionate]
CAS:1264-62-6
MF:C43H75NO16
MW:862.05
EINECS:215-033-8
Product Categories:ERYPED;Organics;Interferes with Protein SynthesisAntibiotics;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Macrolides;Mechanism of Action;Spectrum of Activity;1264-62-6
Mol File:1264-62-6.mol
Erythromycin ethylsuccinate Chemical Properties
Melting point 219-224 C
Boiling point 778.19°C (rough estimate)
density 1.1417 (rough estimate)
refractive index 1.5280 (estimate)
Fp >110°(230°F)
storage temp. Sealed in dry,Room Temperature
solubility ethanol: soluble50mg/mL
form solid
pka13.09±0.70(Predicted)
color white
Water Solubility Freely soluble in organic solvents, practically insoluble in water
Stability:Hygroscopic
CAS DataBase Reference1264-62-6
Safety Information
Hazard Codes Xn,Xi
Risk Statements 42/43-36/37/38
Safety Statements 36-26
WGK Germany 2
RTECS WM9800000
HS Code 29419000
Hazardous Substances Data1264-62-6(Hazardous Substances Data)
ToxicityLD50 oral in mouse: > 10gm/kg
MSDS Information
ProviderLanguage
Erythromycin ethylsuccinate English
SigmaAldrich English
Erythromycin ethylsuccinate Usage And Synthesis
Chemical PropertiesERYTHROMYCIN ETHYLSUCCINATE is crystals
Usesantibacterial
UsesA broad spectrum antibiotic commonly targeting bacteria responsible for respiratory tract infections
Brand nameE-Mycin (Pharmacia & Upjohn); E.E.S. (Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin (Wyeth).
General DescriptionErythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2'-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether.
Erythromycin ethylsuccinate Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->Succinic anhydride-->Erythromycin

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