(S)-(+)-1-Methoxy-2-propanol

(S)-(+)-1-Methoxy-2-propanol
  • CAS No.:26550-55-0
Other grades of this product :
(S)-(+)-1-Methoxy-2-propanol Basic information
Product Name:(S)-(+)-1-Methoxy-2-propanol
Synonyms:(S)-(+)-PROPYLENE GLYCOL 1-METHYL ETHER;(S)-(+)-1-METHOXY-2-PROPANOL;(S)-1-METHOXY-2-PROPANOL;(S)-2-HYDROXY-1-METHOXYPROPANE;(S)-(+)-1-METHOXY-2-PROPANOL 98%;(S)-(+)-1-Methoxy-2-propanol,99%;(S)-(+)-1-Methoxy-2-propanol, 99% 1ML;(S)-(+)-1-Methoxy-2-propanol, 99% 5ML
CAS:26550-55-0
MF:C4H10O2
MW:90.12
EINECS:
Product Categories:Chiral Compound;CHIRAL COMPOUNDS;chiral
Mol File:26550-55-0.mol
(S)-(+)-1-Methoxy-2-propanol Chemical Properties
Melting point -84.2°C (estimate)
Boiling point 118-119 °C
alpha 20 º (c=10, CHCl3)
density 0.921 g/mL at 20 °C (lit.)
refractive index n20/D 1.403
Fp 33 °C
storage temp. Sealed in dry,2-8°C
form Liquid
pka14.49±0.20(Predicted)
color Clear colorless
optical activity[α]20/D +22±2°, c = 10% in chloroform
BRN 1718940
InChIKeyARXJGSRGQADJSQ-BYPYZUCNSA-N
CAS DataBase Reference26550-55-0
Safety Information
Hazard Codes F
Risk Statements 10-15
Safety Statements 24-43-7/8-16
RIDADR UN 3092 3/PG 3
WGK Germany 3
HazardClass 3
PackingGroup 
HS Code 29094990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(S)-(+)-1-Methoxy-2-propanol Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
Uses(S)-(+)-1-Methoxy-2-propanol can be used as a reactant to prepare:
  • (S)-1-methoxypropan-2-yl 4-methylbenzenesulfonate by reacting with tosyl chloride in the presence of pyridine.
  • Thiazolopyridine urea derivatives.
  • Quinazoline derivatives as potential inhibitors of EGFR/HER-2 tyrosine kinases.
Purification MethodsWash the ethers with aqueous NaHCO3 in the presence of solid NaCl, dry them with MgSO4 and fractionally distil them. The RS-acetate [108-65-6] M 132.2 has b 145-146o/atm. The R(+) and S(-) enantiomers have [] D ±20.5o (c 10, H2O). [Beilstein 1 II 536, 1 III 2146, 1 IV 2471.]

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