2-Thiophenecarboxylic acid

2-Thiophenecarboxylic acid
  • CAS No.:527-72-0
Other grades of this product :
2-Thiophenecarboxylic acid Basic information
Uses
Product Name:2-Thiophenecarboxylic acid
Synonyms:2-Thenoic Acid 2-Thiophenic Acid Thiophene-2-carboxylic acid;LABOTEST-BB LT02016392;AKOS B022791;AKOS BBS-00003739;ALPHA-THENOIC ACID;2-THENOIC ACID;2-THIOPHENIC ACID;2-THIOPHENECARBOXYLIC ACID
CAS:527-72-0
MF:C5H4O2S
MW:128.15
EINECS:208-423-4
Product Categories:Building Blocks;C4 to C6;Heterocyclic Compounds;Miscellaneous;Chemical Synthesis;Heterocyclic Building Blocks;Thiophenes;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Thiophene&Benzothiophene;Organic acids;Building Blocks;Heterocyclic Building Blocks
Mol File:527-72-0.mol
2-Thiophenecarboxylic acid Chemical Properties
Melting point 125-127 °C(lit.)
Boiling point 260 °C(lit.)
density 1.42
refractive index 1.5160 (estimate)
Fp 259-261°C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Acetone (Slightly), Chloroform (Slightly)
form solid
pka3.49(at 25℃)
color White to Off-White
Water Solubility 80 g/L (20 ºC)
Merck 14,9354
BRN 110150
InChIKeyQERYCTSHXKAMIS-UHFFFAOYSA-N
CAS DataBase Reference527-72-0(CAS DataBase Reference)
NIST Chemistry Reference2-Thiophenecarboxylic acid(527-72-0)
EPA Substance Registry System2-Thiophenecarboxylic acid (527-72-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS XM8330200
Hazard Note Irritant
TSCA Yes
HS Code 29349990
MSDS Information
ProviderLanguage
Thiophene-2-carboxylic acid English
SigmaAldrich English
ACROS English
ALFA English
2-Thiophenecarboxylic acid Usage And Synthesis
Uses2-Thenoic Acid, is a sulfur-containing heterocyclic compound, used in the synthesis of pharmaceutical and biologically active compounds. It is also shown to be utilized by presumptive Rhodococcus bacterium in soil, as a sole source of carbon.
Chemical Propertieswhite to light yellow crystal powder
Uses2-Thenoic Acid, is a sulfur-containing heterocyclic compound, used in the synthesis of pharmaceutical and biologically active compounds. It is also shown to be utilized by presumptive Rhodococcus bacterium in soil, as a sole source of carbon.
DefinitionChEBI: A thiophenecarboxylic acid in which the carboxy group is located at position 2.
Synthesis Reference(s)The Journal of Organic Chemistry, 30, p. 3520, 1965 DOI: 10.1021/jo01021a055
Purification MethodsCrystallise the acid from water and dry it in a vacuum. The amide has m 181o(from H2O) and pK2 5 10.54(50% aqueous dioxane). [Beilstein 18 H 289, 18 I 438, 18 II 269, 18 III/IV 4011, 18/6 V 158.]

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