3-ALLYLSALICYLALDEHYDE

CAS No.：24019-66-7

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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3-ALLYLSALICYLALDEHYDE Basic information

Product Name:	3-ALLYLSALICYLALDEHYDE
Synonyms:	2-Hydroxy-3-allylbenzaldehyde;3-ALLYL-2-HYDROXY-BENZALDEHYDE;3-ALLYL SALCYLALDEHYDE;3-ALLYLSALICYLALDEHYDE;AKOS BBS-00003205;2-HYDROXY-3-(2-PROPENYL)-BENZALDEHYDE;ASINEX-REAG BAS 02801117;Salicylaldehyde, 3-allyl-
CAS:	24019-66-7
MF:	C10H10O2
MW:	162.19
EINECS:
Product Categories:	Intermediate;Pyridines;Aromatic Aldehydes & Derivatives (substituted);pharmacetical;aldehydes;Aromatics;C10 to C21;Carbonyl Compounds
Mol File:	24019-66-7.mol

3-ALLYLSALICYLALDEHYDE Chemical Properties

Melting point	45 °C
Boiling point	248.88°C (rough estimate)
density	1.099 g/mL at 25 °C (lit.)
refractive index	n20/D 1.5645
Fp	224 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Soluble in chloroform.
pka	8.50±0.10(Predicted)
form	Oil
color	Light Yellow to Yellow
Sensitive	Air Sensitive
CAS DataBase Reference	24019-66-7(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37
WGK Germany	3
HazardClass	IRRITANT
HS Code	29124990

MSDS Information

3-ALLYLSALICYLALDEHYDE Usage And Synthesis

Chemical Properties	Light Yellow Liquid
Uses	3-Allyl Salicylaldehyde is a synthetic intermediate for the sythesis of 3-aminoflavones. Flavonoids have been studied for their antiproliferative activity and in vitro cytotoxicity. Used in the prepar ation of oxazole derivatives. Used in the preparation of imidazole scaffold-based 2-substituted benzofurans for application against human tumor cell lines. Also a reagent in the synthesis of antioxida nt and antimicrobial novel chalcones.
Uses	3-Allylsalicylaldehyde is a synthetic intermediate for the synthesis of 3-aminoflavones. Flavonoids have been studied for their antiproliferative activity and in vitro cytotoxicity. It is used in the preparation of oxazole derivatives and also imidazole scaffold-based 2-substituted benzofurans for application against human tumor cell lines. It is a reagent in the synthesis of antioxidant and antimicrobial novel chalcones.

3-ALLYLSALICYLALDEHYDE Preparation Products And Raw materials

Raw materials

Ethyl acetate-->Potassium carbonate-->Acetone-->Salicylaldehyde-->Allyl bromide

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