Other grades of this product :
| 3-Acetylindole Basic information |
| 3-Acetylindole Chemical Properties |
| Melting point | 188-192 °C (lit.) | | Boiling point | 284.68°C (rough estimate) | | density | 1.1202 (rough estimate) | | refractive index | 1.6070 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO; Dichloromethane; Methanol; | | form | Powder | | pka | 15.38±0.30(Predicted) | | color | Yellow to light brown | | BRN | 122579 | | CAS DataBase Reference | 703-80-0(CAS DataBase Reference) | | NIST Chemistry Reference | Ethanone, 1-(1h-indol-3-yl)-(703-80-0) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | OB4520000 | | HazardClass | IRRITANT | | HS Code | 29339990 |
| 3-Acetylindole Usage And Synthesis |
| Chemical Properties | yellow to light brown powder | | Uses | Reactant for preparation of:• ;Indole derivatives as antitumor agents1• ;Endothelin-1 antagonists2• ;Oncrasin-1 derivatives as inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities3• ;Inhibitors of hepatitis C NS3/4A serine protease4• ;Antibacterial agens against MDR Staphylococcus aureus strains5• ;Antimalarial agents6• ;Anti-bovine viral diarrhea virus (BVDV) agents7• ;HIV-1 integrase inhibitors8• ;Inhibitors of NF-κB transcription regulation related to TNF-α cytokine release9 | | Uses | Reactant for preparation of:- Indole derivatives as antitumor agents
- Endothelin-1 antagonists
- Oncrasin-1 derivatives as inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities
- Inhibitors of hepatitis C NS3/4A serine protease
- Antibacterial agens against MDR Staphylococcus aureus strains
- Antimalarial agents
- Anti-bovine viral diarrhea virus (BVDV) agents
- HIV-1 integrase inhibitors
- Inhibitors of NF-κB transcription regulation related to TNF-α cytokine release
| | Uses | 3-Acetylindole can be used as anti-fungal agents. | | Purification Methods | Recrystallise the indole from MeOH or *C6H6 containing a little EtOH. The phenylureido derivative has m 154o. [Baker J Chem Soc 461 1946, Beilstein 21/8 V 297.] |
| 3-Acetylindole Preparation Products And Raw materials |
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