Other grades of this product :
| Propitocaine hydrochloride Basic information |
| Propitocaine hydrochloride Chemical Properties |
| Melting point | 168-170°C | | storage temp. | 2-8°C | | solubility | Freely soluble in water and in ethanol (96 per cent), very slightly soluble in acetone | | form | neat | | color | White to Off-White | | Merck | 14,7743 | | InChIKey | BJPJNTKRKALCPP-UHFFFAOYSA-N | | CAS DataBase Reference | 1786-81-8(CAS DataBase Reference) |
| WGK Germany | 3 | | RTECS | UG5775000 | | HS Code | 29242990 |
| Propitocaine hydrochloride Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | antibacterial | | Uses | Propitocaine hydrochloride is a local anesthetic of the amino amide type,it is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.
| | Uses | Anesthetic (local). | | Definition | ChEBI: The monohydrochloride salt of prilocaine. | | Brand name | Citanest (AstraZeneca). | | Biological Functions | Prilocaine hydrochloride (Citanest) is an amide
anesthetic whose onset of action is slightly longer than
that of lidocaine; its duration of action is comparable.
Prilocaine is 40% less toxic acutely than lidocaine, making
it especially suitable for regional anesthetic techniques.
It is metabolized by the liver to orthotoluidine,
which when it accumulates, can cause conversion of hemoglobin
(HB+++ to methemoglobin (HB+++. Oxygen
transport is impaired in the presence of methemoglobinemia.
Treatment involves the use of reducing agents,
such as methylene blue, given intravenously, to reconvert
methemoglobin to hemoglobin. | | Contact allergens | Prilocaine in a local anesthetic of the amide group. It
can induce allergic contact dermatitis, particularly
from EMLA? cream. |
| Propitocaine hydrochloride Preparation Products And Raw materials |
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