1-Bromoadamantane

1-Bromoadamantane
  • CAS No.:768-90-1
Other grades of this product :
1-Bromoadamantane Basic information
Product Name:1-Bromoadamantane
Synonyms:1-bromoadmantance;1-Bromoadamantane,99%;11 -BROMOADAMANTANE;3-Bromoadamantane;1-Bromoadamantane,1-Adamantyl bromide;1-BroMoadaMantan;1-broMine adaMantanone;1-BROMOADAMANTANE FOR SYNTHESIS
CAS:768-90-1
MF:C10H15Br
MW:215.13
EINECS:212-200-7
Product Categories:Adamantanes;768-90-1
Mol File:768-90-1.mol
1-Bromoadamantane Chemical Properties
Melting point 116-118 °C (lit.)
Boiling point 248.79°C (rough estimate)
density 1.2686 (rough estimate)
refractive index 1.6411 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Powder
color White to yellow
Water Solubility It is soluble in organic solvents and insoluble in water.
Sensitive Moisture Sensitive
BRN 1098857
InChIKeyVQHPRVYDKRESCL-UHFFFAOYSA-N
CAS DataBase Reference768-90-1(CAS DataBase Reference)
NIST Chemistry Reference1-Bromoadamantane(768-90-1)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
8-10-23
HS Code 29035990
MSDS Information
ProviderLanguage
1-Bromotricyclo[3.3.1.1(3,7)]decane English
ACROS English
SigmaAldrich English
ALFA English
1-Bromoadamantane Usage And Synthesis
Chemical PropertiesWHITE TO ALMOST WHITE CRYSTALS OR CRYST. POWDER
Uses1-Bromoadamantane shows some anti-viral activity due to the adamantane structure. In addition it shows anti-microbial activity and cytotoxic application.
Usesuse: Amantadine, Rimantadine, Somantadine, Tromantadine
Uses1-Bromoadamantane is an important intermediate, used in synthesizing medicines and new materials etc.
Application1-Bromoadamantane was used in the synthesis of a new organic–organic nanoscale composite thin-film dielectric.1-Bromoadamantane forms inclusion complexes with α-, β-, and γ-cyclodextrins. It causes the alkylation of Co(II) complexes of β-diketones.
Synthesis Reference(s)The Journal of Organic Chemistry, 45, p. 5239, 1980 DOI: 10.1021/jo01314a003
General Description1-Bromoadamantane forms inclusion complexes with α-, β-, and γ-cyclodextrins. It causes the alkylation of Co(II) complexes of β-diketones.
Purification MethodsIf coloured, dissolve it in CCl4, wash with H2O, treat with charcoal, dry (CaCl2), filter and evaporate to dryness. Dissolve the residue in a small volume of MeOH and cool in a CO2/trichloroethylene bath and collect the crystals. Sublime it at 90-100o/water pump vacuum. [Stetter et al. Chem Ber 92 1629 1959, Schleyer & Nicholas J Am Chem Soc 83 2700 1961, Beilstein 5 III 469.]

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