2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid

CAS No.：1256584-73-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Basic information

Product Name:	2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
Synonyms:	2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid;2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid-7;4-Ethyl-3-iodo-α,α-dimethylbenzeneacetic acid;4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid;2-(3-Iodo-4-ethylphenyl)-2-methylpropionic acid;Alecensa intermediate;Alectinib Impurity 14;Benzeneacetic acid, 4-ethyl-3-iodo-α,α-dimethyl-
CAS:	1256584-73-2
MF:	C12H15IO2
MW:	318.15
EINECS:
Product Categories:
Mol File:	1256584-73-2.mol

2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Chemical Properties

Boiling point	369.6±27.0 °C(Predicted)
density	1.547±0.06 g/cm3(Predicted)
pka	4.32±0.11(Predicted)

Safety Information

MSDS Information

2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Usage And Synthesis

Uses	2-?(4-?Ethyl-?3-?iodophenyl)?-?2-?methylpropanoic Acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.

2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Preparation Products And Raw materials

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