4-Hydroxyquinoline

4-Hydroxyquinoline
  • CAS No.:611-36-9
Other grades of this product :
4-Hydroxyquinoline Basic information
Product Name:4-Hydroxyquinoline
Synonyms:QUINOLIN-4-OL;QUINOLIN-4(1H)-ONE;KYNURINE;4-hydroxy-quinolin;1H-Quinolin-4-one;Quinoline, 4-hydroxy-;4-Hydroxyquinoline98%;4-Quinolinol,4-Hydroxyquinoline
CAS:611-36-9
MF:C9H7NO
MW:145.16
EINECS:210-268-2
Product Categories:Building Blocks;C8 to C10;Quinoline&Isoquinoline;Quinolines;Chemical Synthesis;Heterocyclic Building Blocks;Alcohols and Derivatives;Heterocycles;Quinolines, Quinazolines and derivatives;Heterocyclic Series;Hydroxyquinolines;quinoline
Mol File:611-36-9.mol
4-Hydroxyquinoline Chemical Properties
Melting point 200-202 °C(lit.)
Boiling point 264.27°C (rough estimate)
density 1.1555 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in methanol.
form Crystalline Powder or Needles
pka2.23, 11.28(at 20℃)
color Light beige to yellow
Water Solubility 4.8g/L(15 ºC)
BRN 1524969
InChIKeyPMZDQRJGMBOQBF-UHFFFAOYSA-N
CAS DataBase Reference611-36-9(CAS DataBase Reference)
NIST Chemistry Reference4-Quinolinol(611-36-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS VC4070000
HS Code 29334900
MSDS Information
ProviderLanguage
4-Quinolinol English
SigmaAldrich English
ACROS English
ALFA English
4-Hydroxyquinoline Usage And Synthesis
Chemical PropertiesLIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES
Uses4-Hydroxyquinolineis a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.
Uses4-Hydroxyquinoline is a medical raw material.
DefinitionChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.
Synthesis Reference(s)Journal of the American Chemical Society, 68, p. 1264, 1946 DOI: 10.1021/ja01211a038
General Description4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.
Biological Activity4-hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity. it shows growth-inhibitory effects against intestinal bacteria. it also can be used as sacrificial scavengers of the photogenerated oxygen species.

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