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| Sesamol Chemical Properties |
| Melting point | 62-65 °C (lit.) | | Boiling point | 113-116°C 2mm | | density | 1.2112 (rough estimate) | | refractive index | 1.4850 (estimate) | | Fp | 113-116°C/2mm | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform, Methanol | | pka | 10.08±0.20(Predicted) | | form | crystalline | | color | off-white to tan | | Water Solubility | slightly soluble | | Sensitive | Light Sensitive | | BRN | 127405 | | InChIKey | LUSZGTFNYDARNI-UHFFFAOYSA-N | | CAS DataBase Reference | 533-31-3(CAS DataBase Reference) | | NIST Chemistry Reference | 1,3-Benzodioxol-5-ol(533-31-3) | | EPA Substance Registry System | Sesamol (533-31-3) |
| Sesamol Usage And Synthesis |
| Description | Sesamol is found in sesame seeds and sesame oil. It is a well-known antioxidant. It has antioxidant, chemoprevention, antimutagenic, and antihepatotoxic activities and can induce the apoptosis of cancer and cardiovascular cells. It can be used in the synthesis of paroxetine.
| | Reference |
- M. A. Ansari, Z. Fatima, S. Hameed, Sesamol: A Natural Phenolic Compound with Promising Anticandidal Potential, Journal of Pathogens, vol. 2014, Article ID 895193
- T. Geetha, B. Rohit, K. Pal, Sesamol: an efficient antioxidant with potential therapeutic benefits, Medicinal Chemistry, 2009, vol. 5, pp. 367-371
| | Chemical Properties | off-white to beige crystalline powder | | Uses | Sesamol is a natural component of sesame oil with antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as
an intermediate in the preparation of antidepressants such as Paroxetine (P205750). | | Uses | Sesamol (Paroxetine Anhydrous EP Impurity B) is a natural component of sesame oil with antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine (P205750). | | Synthesis Reference(s) | Tetrahedron Letters, 19, p. 3085, 1978 DOI: 10.1016/S0040-4039(01)94947-0 | | General Description | Sesamol, a principal phytophenol of sesame oil lignans, is typically used as a dietary compound.(10) |
| Sesamol Preparation Products And Raw materials |
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