N-Boc-pyrroline

N-Boc-pyrroline
  • CAS No.:73286-70-1
Other grades of this product :
N-Boc-pyrroline Basic information
Product Name:N-Boc-pyrroline
Synonyms:2,5-DIHYDRO-PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;N-BOC-2,5-DIHYDROPYRROLE;N-BOC-PYRROLINE;1-tert-Butoxycarbonylpyrroline;2,5-Dihydro-1H-pyrrole-1-carboxylic acid 1,1-dimethylethyl ester;n-boc-2,5-dihydro-1h-pyrrole;tert-Butyl 2H-pyrrole-1(5H)-carboxylate;2,5-Dihydro-1H-pyrrole, N-BOC protected
CAS:73286-70-1
MF:C9H15NO2
MW:169.22
EINECS:
Product Categories:Pyrroles & Indoles;Pyrrolidine series;Pyrroles & Indoles;N-Boc-3-pyrroli
Mol File:73286-70-1.mol
N-Boc-pyrroline Chemical Properties
Melting point 40.0 to 44.0 °C
Boiling point 208 °C(lit.)
density 0.981 g/mL at 25 °C(lit.)
refractive index n20/D 1.458(lit.)
Fp 178 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Low Melting Solid or Liquid
pka-1.46±0.20(Predicted)
color White to yellow
Water Solubility Slightly soluble in water.
InChIKeyYEBDZDMYLQHGGZ-UHFFFAOYSA-N
CAS DataBase Reference73286-70-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
N-Boc-pyrroline Usage And Synthesis
Chemical PropertiesWhite to yellow low melting solid or liquid
UsesUsed in a synthesis of ?-aryl-GABA analogues by Heck arylation with arenediazonium salts, as well as synthesize aryl pyrrolizidines. N-Boc-pyrroline has also been utilized in the synthesis of various antibacterial compounds. It has also been used in the preparation of regioisomeric 3-hydroxyisoxazolinyl prolines which are medicinally active.
General DescriptionN-Boc-2,5-dihydro-1H-pyrrole, also known as tert-butyl 2,5-dihydro-1H-pyrrole-1-carboxylate, can be synthesized from N-boc-diallylamine.

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