2-Fluorobenzoyl chloride
2-Fluorobenzoyl chloride
  • CAS No.:393-52-2
Other grades of this product :
2-Fluorobenzoyl chloride Basic information
Product Name:2-Fluorobenzoyl chloride
Synonyms:2-Fluorbenzoylchlorid;2-Fluorobenzoyl chlo;2-Fluorobenzoyl chloride, 97% 100ML;2-Fluorobenzoyl chloride, 97% 25ML;2-Fluorobenzenecarbonyl Chloride;NSC 88304;2-Fluorobenzoyl;Orthofluorine benzoyl chloride
CAS:393-52-2
MF:C7H4ClFO
MW:158.56
EINECS:206-887-2
Product Categories:Acid Halides;Aryl Fluorinated Building Blocks;Building Blocks;C7;Carbonyl Compounds;Chemical Synthesis;Fluorobenzene;Acid Halides;Aromatics;Miscellaneous Reagents;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Carbonyl Compounds;Organic Building Blocks
Mol File:393-52-2.mol
2-Fluorobenzoyl chloride Chemical Properties
Melting point 4 °C (lit.)
Boiling point 90-92 °C/15 mmHg (lit.)
density 1.328 g/mL at 25 °C (lit.)
refractive index n20/D 1.536(lit.)
Fp 180 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly)
form Liquid
Specific Gravity1.328
color Clear colorless to faintly colored
Water Solubility Decomposition
Sensitive Lachrymatory
BRN 636864
CAS DataBase Reference393-52-2(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoyl chloride, 2-fluoro-(393-52-2)
EPA Substance Registry Systemo-Fluorobenzoyl chloride (393-52-2)
Safety Information
Hazard Codes C
Risk Statements 34-37-36/37-14
Safety Statements 26-36/37/39-45-28A-27
RIDADR UN 3265 8/PG 2
WGK Germany 3
RTECS DM6640000
10-19-21
Hazard Note Corrosive/Lachrymatory
TSCA Yes
HazardClass 8
PackingGroup II
HS Code 29163900
Hazardous Substances Data393-52-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
o-Fluorobenzoyl chloride English
SigmaAldrich English
ACROS English
ALFA English
2-Fluorobenzoyl chloride Usage And Synthesis
Chemical Propertiesclear colorless to faintly colored liquid
Uses2-Fluorobenzoyl Chloride (cas# 393-52-2) is a compound useful in organic synthesis.
Uses2-Fluorobenzoyl chloride has been used in the preparation of 3-(N-Hydroxycarbamimidoyl)-benzoic acid methyl ester. It has been used to develop an hollow-fiber liquid phase microextraction with in situ derivatization method coupled with HPLC-UV for the determination of metformin hydrochloride in biological fluids.
General DescriptionColorless liquid.
Air & Water ReactionsDecomposes in water to form HCl with generation of heat
Reactivity Profile2-Fluorobenzoyl chloride is sensitive to moisture. Incompatible with water, alcohol, bases (including amines) and with oxidizing agents . May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Fire Hazard2-Fluorobenzoyl chloride is combustible.
2-Fluorobenzoyl chloride Preparation Products And Raw materials
Raw materials2-Fluorotoluene
Preparation ProductsFLURAZEPAM-->2-Fluorobenzoic acid-->2,4'-Difluorobenzophenone-->Ataluren (PTC124)

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