Other grades of this product :
| 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Basic information |
| Product Name: | 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide | | Synonyms: | LOIRD;2-hydroxy-n-(4-hydroxyphenyl)-benzamide;2-hydroxy-n-(4-hydroxyphenyl)-benzamid;4’-hydroxy-salicylanilid;4’-hydroxysalicylanilide;4-Hydroxysalicylanilide;auxobil;OSALMID | | CAS: | 526-18-1 | | MF: | C13H11NO3 | | MW: | 229.23 | | EINECS: | 208-385-9 | | Product Categories: | | Mol File: | 526-18-1.mol |
| 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Chemical Properties |
| Melting point | 179° | | Boiling point | 371.13°C (rough estimate) | | density | 1.2084 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.5500 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | pka | 8.40±0.30(Predicted) | | Water Solubility | 916mg/L at 25℃ | | LogP | 2.47 at 25℃ | | CAS DataBase Reference | 526-18-1(CAS DataBase Reference) | | EPA Substance Registry System | Osalmid (526-18-1) |
| 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Usage And Synthesis |
| Biochem/physiol Actions | Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown. |
| 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Preparation Products And Raw materials |
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