2-Bromo-2′-hydroxyacetophenone

CAS No.：2491-36-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-Bromo-2′-hydroxyacetophenone Basic information

Product Name:	2-Bromo-2′-hydroxyacetophenone
Synonyms:	2-Bromo-2'-hydroxyacetophenone ,97%;2-Bromo-2'-hydroxyacetophenone, 2-Bromo-1-(2-hydroxyphenyl)ethan-1-one, 2-(Bromoacetyl)phenol;2-broMo-1-(2-hydroxyphenyl)ethan-1-one;2-Bromo-2'-hydroxyacetophenone 97%;JR-8498, 2-Bromo-1-(2-hydroxyphenyl)ethanone, 97%;2-bromo-1-(2-hydroxyphenyl)-ethanon;2-HYDROXYPHENACYL BROMIDE;2-BROMO-1-(2-HYDROXYPHENYL)ETHANONE
CAS:	2491-36-3
MF:	C8H7BrO2
MW:	215.04
EINECS:
Product Categories:	Intermediate of Neticonazole Hydrochloride;API intermediates;Aromatics;C7 to C8;Carbonyl Compounds;Ketones
Mol File:	2491-36-3.mol

2-Bromo-2′-hydroxyacetophenone Chemical Properties

Melting point	44-48 °C(lit.)
Boiling point	152-158 °C(Press: 18 Torr)
density	1.622±0.06 g/cm3(Predicted)
Fp	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Chloroform, Methanol
pka	7.63±0.30(Predicted)
form	Solid
color	Yellow
Sensitive	Lachrymatory
CAS DataBase Reference	2491-36-3(CAS DataBase Reference)

Safety Information

Hazard Codes	C
Risk Statements	22-34
Safety Statements	26-36/37/39-45
RIDADR	UN 3263 8/PG 2
WGK Germany	3
RTECS	KM5556400
Hazard Note	Corrosive/Lachrymatory/Keep Cold
HazardClass	8
PackingGroup	II
HS Code	29147000

MSDS Information

Provider	Language
SigmaAldrich	English

2-Bromo-2′-hydroxyacetophenone Usage And Synthesis

Chemical Properties	Off-White Powder
Uses	2-Bromo-2′-hydroxyacetophenone is used as a pharmaceutical intermediate.

2-Bromo-2′-hydroxyacetophenone Preparation Products And Raw materials

Raw materials	Acetic acid-->Government regulation-->2'-Hydroxyacetophenone-->Ethanone, 1-[2-(acetyloxy)phenyl]-2-bromo--->Phenyl bromoacetate-->2-HYDROXYACETOPHENONE-->Phenol
Preparation Products	5-Bromo-2-hydroxyacetophenone-->2-Bromo-4'-hydroxyacetophenone-->2-BROMO-1-(5-BROMO-2-HYDROXYPHENYL)ETHANONE-->3-(BROMOMETHYL)-1,2-BENZISOXAZOLE

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