Product

(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

CAS No.：28416-82-2

Other grades of this product :

(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Basic information

Product Name:	(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid
Synonyms:	impurity J;6a,9a-Difluoro-11b,17a-dihydroxy-16a-methylpregna-3-oxo-1,4-diene-17b-carboxylic Acid;Fluticasone 17b-Carboxylic Acid;6A,9A-DIFLUORO-11SS,17A-DIHYDROXY-3-OXOANDROSTA-1,4-DIENE-17SS-CARBOXYLIC ACID;ANDROSTA-1,4-DIENE-17-CARBOXYLIC ACID,6,9-DIFLUORO-11,17- DIHYDROXY-16-METHYL-3-OXO-,(6ALPHA,11BETA,16ALPHA,17ALPHA)-;ANDROSTA-1,4-DIENE-17-CARBOXYLIC ACID,6,9-DIFLUORO-11,17- DIHYDROXY-16-METHYL-3-OXO-,(6A,11SS,16A,17A)-;(6a,11,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxo-androsta-1,4-diene-17-carboxylic Acid;6a,9a-Difluoro-11,17a-dihydroxy-16a-methylpregna-3-oxo-1,4-diene-17-carboxylic Acid
CAS:	28416-82-2
MF:	C21H26F2O5
MW:	396.42
EINECS:	206-597-6
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File:	28416-82-2.mol

(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Chemical Properties

Melting point	303-305°C
Boiling point	568.4±50.0 °C(Predicted)
density	1.38±0.1 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	3.49±0.70(Predicted)
color	White to Off-White

Safety Information

HS Code

2937220000

MSDS Information

(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Usage And Synthesis

Description	Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid fluticasone propionate .
Chemical Properties	White Solid
Uses	The major metabolite of Fluticasone. Anti-inflammatory agent.
Uses	Fluticasone intermediate. Anti-inflammatory agent

(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Preparation Products And Raw materials

Preparation Products

FLUTICASONE PROPIONATE INTERMEDIATE

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