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| Methyl carbamate Basic information |
| Product Name: | Methyl carbamate | | Synonyms: | MCM;MECB;METHYLURETHANE;METHYL CARBAMATE;CARBAMIC ACID METHYL ESTER;p85-alpha;PI3K (p110-α/p85-α), active, His tagged from mouse and human;p55-gamma | | CAS: | 598-55-0 | | MF: | C2H5NO2 | | MW: | 75.07 | | EINECS: | 209-939-2 | | Product Categories: | | Mol File: | 598-55-0.mol |
| Methyl carbamate Chemical Properties |
| Melting point | 56-58 °C (lit.) | | Boiling point | 176-177 °C (lit.) | | density | 1,14 g/cm3 | | refractive index | 1.4125 | | Fp | 93 °C | | storage temp. | Inert atmosphere,Room Temperature | | solubility | 700 g/L (20°C) | | pka | 13.37±0.50(Predicted) | | form | Adhering Crystals | | color | White | | PH | 6-8 (50g/l, H2O, 20℃) | | Water Solubility | 700 g/L (20 ºC) | | Sensitive | Moisture Sensitive | | Merck | 14,6036 | | BRN | 635779 | | CAS DataBase Reference | 598-55-0(CAS DataBase Reference) | | IARC | 3 (Vol. 12, Sup 7) 1987 | | NIST Chemistry Reference | Carbamic acid, methyl ester(598-55-0) | | EPA Substance Registry System | Methyl carbamate (598-55-0) |
| Methyl carbamate Usage And Synthesis |
| Chemical Properties | WHITE ADHERING CRYSTALS | | Uses | Methyl carbamate was used in the synthesis of protected aminocyclopropanes. | | Preparation | Methyl carbamate was synthesized by the following preparation. MDI (5.00 g,0.020mol) and 100 ml of dried acetone were weighed into a Ng-filled three-neck flask.Methanol (5 g, an excess amount) is added dropwise to the stirred MDI solution in the flask,and then the solution was heated to 56 C. After 24 hrs， the reaction mixture was cooled down to room temperature and evaporated to give a crude solid at about 100% yield. The following recrystallization procedure gave 3.1 g of a white solid (0.012 mol，60% yield). The disappearance of FT-IR stretching band of the isocyanate group (-N=C=O, 2280 cm') confirmed that the reaction was complete. | | Definition | ChEBI: Methyl carbamate is a carbamate ester resulting from the formal condensation of the carboxy group of carbamic acid with methanol. | | General Description | White crystals. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | Methyl carbamate is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. | | Fire Hazard | Flash point data for Methyl carbamate are not available; however, Methyl carbamate is probably combustible. | | Safety Profile | Poison by ingestion and
intraperitoneal routes. Questionable
carcinogen with experimental carcinogenic
and tumorigenic data. Mutation data
reported. When heated to decomposition it
emits toxic fumes of NOx. See also
CARBAMATES. | | Purification Methods | Crystallise the carbamate from *benzene or distil it. [Beilstein 3 H 21.] |
| Methyl carbamate Preparation Products And Raw materials |
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