Ethyl acetimidate hydrochloride

Ethyl acetimidate hydrochloride
  • CAS No.:2208-07-3
Other grades of this product :
Ethyl acetimidate hydrochloride Basic information
Product Name:Ethyl acetimidate hydrochloride
Synonyms:EAH;ETHYL ACETAMIDATE HCL;ETHYL ACETIMIDATE HYDROCHLORIDE;1-ethoxyethylideneammonium chloride;ACETIMIDIC ACID ETHYL ESTER;ETHYL ACETIMIDATE HCL;Ethyl acetimidate hydrochloride, 98.5%;EthyliminoacetateHCl
CAS:2208-07-3
MF:C4H10ClNO
MW:123.58
EINECS:218-631-7
Product Categories:Amidates/Imidates;Nitrogen Compounds;Organic Building Blocks
Mol File:2208-07-3.mol
Ethyl acetimidate hydrochloride Chemical Properties
Melting point 112-114 °C(lit.)
storage temp. Inert atmosphere,Room Temperature
solubility water: soluble50mg/mL, clear, colorless
form Crystalline Powder
color White
Water Solubility Soluble in water (50mg/L).
Sensitive Moisture Sensitive
BRN 3552401
Stability:Hygroscopic, Moisture Sensitive
InChIKeyWGMHMVLZFAJNOT-UHFFFAOYSA-N
CAS DataBase Reference2208-07-3(CAS DataBase Reference)
EPA Substance Registry SystemEthanimidic acid, ethyl ester, hydrochloride (2208-07-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
3-10-21
TSCA Yes
HazardClass IRRITANT
HS Code 29252900
MSDS Information
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Ethyl acetimidate hydrochloride Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
UsesEthyl acetimidate hydrochloride was used in preparation of amidinated carbonic anhydrase via chemical modification of human erythrocyte carbonic anhydrase. It was also used in synthesis of methyl 2-methyl-2-thiazoline-4-carboxylate hydrochloride.
Purification MethodsRecrystallise the hydrochloride by dissolving it in the minimum volume of super dry EtOH and adding dry Et2O or from dry Et2O. Dry it in a vacuum and store it in a vacuum desiccator with P2O5. Alternatively it could be crystallised from EtOH (containing a couple of drops of ethanolic HCl) and adding dry Et2O. Filter and dry it in a vacuum desiccator over H2SO4 and NaOH. [Pinner Chem Ber 16 1654 1883, Glickman & Cope J Am Chem Soc 67 1020 1945, Chaplin & Hunter J Chem Soc 1118 1937, McElvain & Schroeder J Am Chem Soc 71 40 1949, McElvain & Tate J Am Chem Soc 73 2233 1951, Methods Enzymol 25 585 1972, Beilstein 2 III 418.]
Ethyl acetimidate hydrochloride Preparation Products And Raw materials
Raw materialsEthyl chloroformate-->Ethanol-->Acetyl chloride-->Hydrochloric acid-->Acetonitrile-->Acetamide

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