Endoxifen

CAS No.：112093-28-4

Other grades of this product :

Endoxifen Basic information

Product Name:	Endoxifen
Synonyms:	(Z)-4-Hydroxy-N-desmethyl Tamoxifen;4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;Endoxifen;Phenol, 4-[(1Z)-1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-butenyl]-;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) see D292043;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) ;(Z)-4-Hydroxy-N-DesMethyl TaMoxifen (Endoxifen);(Z)-Endoxifen
CAS:	112093-28-4
MF:	C25H27NO2
MW:	373.49
EINECS:
Product Categories:	Inhibitors;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics
Mol File:	112093-28-4.mol

Endoxifen Chemical Properties

Melting point	127-129°C
Boiling point	519.3±50.0 °C(Predicted)
density	1.099±0.06 g/cm3(Predicted)
storage temp.	Amber Vial, -86°C Freezer, Under Inert Atmosphere
pka	10.36±0.15(Predicted)

Safety Information

MSDS Information

Endoxifen Usage And Synthesis

Chemical Properties	Off-White to Pink Solid
Uses	A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca
Uses	A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

Endoxifen Preparation Products And Raw materials

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