2-Chloro-2',4'-difluoroacetophenone

CAS No.：51336-94-8

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2-Chloro-2',4'-difluoroacetophenone Basic information

Description

Product Name:	2-Chloro-2',4'-difluoroacetophenone
Synonyms:	2,4-difluorophenacyl chloride ,2-chloro-1-(2,4-difluorophenyl)ethanone;Chloromethyl(2,4-difluorophenyl) ketone;2-CHLORO-2',4'-DIFLUOROACETOPHEONE;2-Bhloro-2',4'-difluoroacetophenone;Ethanone,2-chloro-1-(2,4-difluorophenyl)-;2-Chloro-2',4'-difluoroacetophenone,98%;2-Chloro-2;[2-(2,4-difluorophenyl)-2-oxoethyl]chloranuide
CAS:	51336-94-8
MF:	C8H5ClF2O
MW:	190.57
EINECS:	620-343-5
Product Categories:	Acetophenone series;Aromatics;C7 to C8;Carbonyl Compounds;Ketones;Inhibitors;blocks;FluoroCompounds;Benzene series
Mol File:	51336-94-8.mol

2-Chloro-2',4'-difluoroacetophenone Chemical Properties

Melting point	44-48 °C(lit.)
Boiling point	240.9±25.0 °C(Predicted)
density	1.3544 (estimate)
Fp	>230 °F
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Slightly)
form	Solid
color	Light Brown
Sensitive	Lachrymatory
BRN	1943217
InChIKey	UENGBOCGGKLVJJ-UHFFFAOYSA-N
CAS DataBase Reference	51336-94-8(CAS DataBase Reference)

Safety Information

Hazard Codes	C,Xi
Risk Statements	34-37
Safety Statements	26-36/37/39-45-25-27
RIDADR	UN 3261 8/PG 2
WGK Germany	3
F	10-21
Hazard Note	Corrosive/Irritant/Lachrymatory
HazardClass	8
PackingGroup	II
HS Code	29147000

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

2-Chloro-2',4'-difluoroacetophenone Usage And Synthesis

Description	2-Chloro-2′,4′-difluoroacetophenone was used in the synthesis of allyl alcohol1. It can also be tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B2.
Chemical Properties	white crystalline powder
Uses	A α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.
Uses	2-Chloro-2′,4′-difluoroacetophenone was used in the synthesis of allyl alcohol.

2-Chloro-2',4'-difluoroacetophenone Preparation Products And Raw materials

Preparation Products

1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]--->Ravuconazole

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