Product

3-benzyl-6-bromo-2-chloroquinoline

CAS No.：654655-68-2

Other grades of this product :

3-benzyl-6-bromo-2-chloroquinoline Basic information

Product Name:	3-benzyl-6-bromo-2-chloroquinoline
Synonyms:	3-benzyl-6-bromo-2-chloroquinoline;6-Bromo-2-chloro-3-(phenylmethyl)quinoline;Bedaquiline Impurity B;Quinoline, 6-bromo-2-chloro-3-(phenylmethyl)-;Bedaquiline Fumarate Impurity 5
CAS:	654655-68-2
MF:	C16H11BrClN
MW:	332.62
EINECS:
Product Categories:	bedaquiline intermediates
Mol File:	654655-68-2.mol

3-benzyl-6-bromo-2-chloroquinoline Chemical Properties

Melting point	111-112℃
Boiling point	435.9±40.0 °C(Predicted)
density	1.482±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	-0.42±0.50(Predicted)

Safety Information

MSDS Information

3-benzyl-6-bromo-2-chloroquinoline Usage And Synthesis

Uses	3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.

3-benzyl-6-bromo-2-chloroquinoline Preparation Products And Raw materials

Preparation Products

3-benzyl-6-bromo-2-methoxyquinoline

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