Product

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL

CAS No.：588-36-3

Other grades of this product :

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Basic information

Product Name:	(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL
Synonyms:	4-AMINO-2-(METHYLTHIO)-5-PYRIMIDINEMETHANOL;4-AMINO-5-HYDROXYMETHYL-2-(METHYLTHIO)PYRIMIDINE;Methioprim;(4-azanyl-2-methylsulfanyl-pyrimidin-5-yl)methanol;(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL;(4-AMINO-2-METHYLSULFANYL-PYRIMIDIN-5-YL)-METHANOL;4-AMINO-2-METHYLMERCAPTO-PYRIMIDINE-4-CARBINOL;(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)ME...
CAS:	588-36-3
MF:	C6H9N3OS
MW:	171.22
EINECS:
Product Categories:	Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds
Mol File:	588-36-3.mol

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Chemical Properties

Melting point	126-127°
Boiling point	408.6±30.0 °C(Predicted)
density	1.38±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	13.08±0.10(Predicted)
color	Off-White to Pale Yellow

Safety Information

HS Code

29335990

MSDS Information

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Usage And Synthesis

Chemical Properties	(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is white cryst powder
Uses	Tumor antagonist in mice.
Uses	(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL is an intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.

(4-AMINO-2-(METHYLTHIO)PYRIMIDIN-5-YL)METHANOL Preparation Products And Raw materials

Raw materials

Ethanol-->Tetrahydrofuran-->Sodium-->Toluene-->Acetic anhydride-->Lithium Aluminum Hydride-->Isopropyl alcohol-->Triethyl orthoformate-->Ethyl cyanoacetate-->Thiourea-->N,N-Dimethylformamide dimethyl acetal

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