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| PYRROLOQUINOLINE QUINONE DISODIUM SALT Basic information |
| Product Name: | PYRROLOQUINOLINE QUINONE DISODIUM SALT | | Synonyms: | disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylat;PQQ, Pyrrolo-quinoline-quinone disodium salt;sodiuM 9-carboxy-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7-dicarboxylate;PQQ disodium;1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylicacid, 4,5-dihydro-4,5-dioxo-, sodium salt;PYRROLOQUINOLINE QUINONE DISODIUM SALTPYRROLOQUINOLINE QUINONE DISODIUM SALT;PQQ Disodium Salt;PYRROLOQUINOLINE QUINONE DISODIUM SALT | | CAS: | 122628-50-6 | | MF: | C14H7N2NaO8 | | MW: | 354.21 | | EINECS: | | Product Categories: | PQQ;122628-50-6 | | Mol File: | 122628-50-6.mol |
| PYRROLOQUINOLINE QUINONE DISODIUM SALT Chemical Properties |
| storage temp. | 2-8°C | | InChIKey | UFVBOGYDCJNLPM-UHFFFAOYSA-L |
| WGK Germany | 3 | | RTECS | UY9454762 | | F | 10-21 |
| PYRROLOQUINOLINE QUINONE DISODIUM SALT Usage And Synthesis |
| Description | Pyrroloquinoline quinone disodium salt is a water-soluble quinone compound that has a strong anti-oxidant capacity. | | Uses | Pyrroloquinoline quinone disodium salt can act as an antioxidant and there is strong evidence that PQQ may play an important role in important pathways of cell signaling. PQQ plays a variety of physiological roles, such as promoting growth and reproduction and providing neurological and cardiovascular protection. | | Application | Pyrroloquinoline quinone disodium salt protects cells from oxidative damage and increases the mitochondrial membrane potential, which is essential for the production of ATP. It also stimulates enzyme activities, such as glutathione peroxidase and glutathione reductase, and prevents lipid peroxidation of human serum. This compound also inhibits radiation-induced cellular damage by preventing DNA strand breakage. It may be effective in treating diseases related to oxidative stress, such as diabetes and cancer. | | Source | Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals. | | Biochem/physiol Actions | In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor. |
| PYRROLOQUINOLINE QUINONE DISODIUM SALT Preparation Products And Raw materials |
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