Halquinol
Halquinol
  • CAS No.:8067-69-4
Other grades of this product :
Halquinol Basic information
Product Name:Halquinol
Synonyms:chlorquinol;HALQUINOL;5-chloroquinolin-8-ol,7-chloroquinolin-8-ol,5,7-dichloroquinolin-8-ol;5-CHLOROQUINOLIN-8-OL;5,7-dichloro-8-quinolinol mixed with 5-chloro-8-quinolinol;5,7-DICHLOROQUINOLIN-8-OL;7-CHLOROQUINOLIN-8-OL;quinolor
CAS:8067-69-4
MF:C9H5ClNOR
MW:178.6
EINECS:1312995-182-4
Product Categories:BENEHALQUI
Mol File:8067-69-4.mol
Halquinol Chemical Properties
Melting point >137*C (dec.)
storage temp. Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Very Slightly)
form Solid
color Brown
JECFA Number85
CAS DataBase Reference8067-69-4(CAS DataBase Reference)
Safety Information
MSDS Information
Halquinol Usage And Synthesis
OriginatorCapitrol,Westwood Squibb
UsesAntiinfective, topical.
UsesHalquinol is an antimicrobial compound belonging to the group of hydroxyl-quinolines indicated for use in poultry and swine. It depresses the activity of the gastro-intestinal tract, causing longer transit time of feed through the intestine, thereby enhancing digestion and absorption of nutrients. It increases weight gain and improve feed conversionprevent and control nonspecific diarrhea or wet dropping in farming animals.
Manufacturing Process8-Quinolinol (mixture of 57-74% 5,7-dichloro-8-hydroxyquinoline, 23-40% 5- chloro-8-hydroxyquinoline and less than 3% 7-chloro-8-hydroxyquinoline) was synthesized by interaction of 8-hydroxyquinoline with sulfuryl chloride in glacial acetic acid at 50°C for 1.5 hours. The reaction mixture was cooled, pH was made 6.0 (by addition NH4OH). The suspension obtained was centrifuged, washed with water and the mixture of chlorohydroxyquinolines was dried.
Brand nameQuinolor (Bristol-Myers Squibb).
Therapeutic FunctionAntibacterial, Antidiarrheal, Antiseborreic
Halquinol Preparation Products And Raw materials
Raw materials8-Hydroxyquinoline-->Sulfuryl chloride

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